Chapter 38. The Degenerative Dementias

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief5,6,
  2. Daniel D. Truong MD, FAAN Head7,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head8 and
  4. Roongroj Bhidayasiri MD, FRCP Director9,10
  1. Irena Rektorová MD, PhD Associate Professor of Neurology1,
  2. Robert Rusina MD Neurologist2,
  3. Jakub Hort MD, PhD Associate Professor of Neurology3 and
  4. Radoslav Matěj MD, PhD Neuropathologist4

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch38

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Rektorová, I., Rusina, R., Hort, J. and Matěj, R. (2009) The Degenerative Dementias, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch38

Editor Information

  1. 5

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 6

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 7

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 8

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 9

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 10

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. 1

    First Department of Neurology, Masaryk University and St Anne's Hospital, Brno, Czech Republic

  2. 2

    Department of Neurology, Thomayer Teaching Hospital and Institute of Postgraduate Education in Medicine, Prague, Czech Republic

  3. 3

    Department of Neurology, Charles University, Teaching Hospital Motol, Prague, Czech Republic

  4. 4

    Department of Pathology and Molecular Medicine, National Laboratory for Diagnostics of Prion Diseases, Thomayer Teaching Hospital, Prague, Czech Republic

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • degenerative dementias;
  • Alzheimer's disease (AD) - most common cause of dementia;
  • dementia with Lewy bodies (DLB) - Parkinson's disease (PD) dementia;
  • vascular dementia (VaD) - most frequent cause of dementia in elderly;
  • cerebrovascular disease and cognitive impairment;
  • frontotemporal dementia (FTD) - common dementia of degenerative origin;
  • Prions (proteinaceous infectious particles) - infectious agents lacking nucleic acids;
  • Creutzfeldt-Jakob disease (CJD) - no distinct socioeconomic incidence pattern


This chapter contains sections titled:

  • Alzheimer's disease

  • Dementia with Lewy bodies and Parkinson's disease dementia

  • Vascular dementia

  • Frontotemporal dementia

  • Prion diseases

  • Creutzfeldt–Jakob disease (CJD)

  • Further reading