Chapter 46. Myoclonus

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. John N. Caviness MD Professor of Neurology1 and
  2. Daniel D. Truong MD, FAAN Head4

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch46

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Caviness, J. N. and Truong, D. D. (2009) Myoclonus, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch46

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. 1

    Mayo Clinic College of Medicine, Scottsdale, AZ, USA

  2. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008

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Keywords:

  • myoclonus, sudden, brief, shock-like, involuntary movements and muscular contractions;
  • clinical neurophysiology, information about myoclonus pathophysiology;
  • myoclonus epidemiology, only study in a defined population from Olmsted County, Minnesota;
  • multichannel surface electromyography (EMG) recording with testing - for long latency EMG responses to nerve stimulation;
  • myoclonus etiological classification scheme - physiologic, essential, epileptic, and symptomatic (secondary);
  • sporadic essential myoclonus - heterogeneous with regard to distribution;
  • major myoclonic disorder features - post-hypoxic myoclonus;
  • multiple system atrophy, manifesting as varying degrees of parkinsonism, ataxia, and autonomic dysfunction;
  • spectrum of lithium-induced myoclonus - with regards to different clinical manifestations of motor cortex hyperexcitability

Summary

This chapter contains sections titled:

  • Introduction

  • Classification

  • Features of major myoclonic disorders

  • Evaluation

  • Treatment

  • Further reading