Chapter 5. Binswanger's Disease

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief3,4,
  2. Daniel D. Truong MD, FAAN Head5,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head6 and
  4. Roongroj Bhidayasiri MD, FRCP Director7,8
  1. Dean A. Le MD, PhD Neurology Consultant1 and
  2. Ferdinando S. Buonanno MD Associate Professor of Neurology2

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch5

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Le, D. A. and Buonanno, F. S. (2009) Binswanger's Disease, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch5

Editor Information

  1. 3

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 4

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 5

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 6

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 7

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 8

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. 1

    Saddleback Memorial Medical Center, Laguna Hills, CA, USA

  2. 2

    Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • Binswanger's disease - Binswanger's encepahlopathy - vascular dementia;
  • Binswanger's disease - ischemic attacks associated progressive dementia;
  • epidemiology - Binswanger's disease onset - after age 50;
  • periventricular white matter lesion appearance in demented patients;
  • pathophysiology - risk factors - hypertension and old age;
  • clinical features - attention and memory function deficits;
  • Binswanger's disease treatment/management - blood pressure control


This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathophysiology

  • Clinical features

  • Treatment/management

  • Further reading