Chapter 65. Acute Bacterial Meningitis

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Sudesh Prabhakar MD, DM Professor Head

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch65

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Prabhakar, S. (2009) Acute Bacterial Meningitis, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch65

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • acute bacterial meningitis (ABM), a fulminant purulent infection of meninges;
  • associated inflamatory reaction of central nervous system (CNS) - altered sensorium, seizures, and raised intracranial pressure (ICP);
  • etiological agent for ABM - age of patients, their immunological status;
  • community-acquired bacterial meningitis (CABM) and nosocomial meningitis;
  • bacterial meningitis, due to S. pneumoniae - associated with pneumonia and sinusitis;
  • S. pneumoniae and N. meningitidis, common bacteria-producing meningitis, colonizing the nasopharynx;
  • bacteria invasion in subarachnoid space (SAS) - producing inflammation and release of tumor necrosis factor (TNF);
  • meninges over cerebral convexities in bacterial meningitis - usually yellowish-green in color;
  • obstruction of foramina of Luschka and Magendie - resulting in communicating hydrocephalus


This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Etiology

  • Pathophysiology

  • Pathology

  • Clinical presentation

  • Diagnosis

  • Differential diagnosis

  • Treatment

  • Prevention

  • Prognosis

  • Complications

  • Further reading