Chapter 71. Mycobacterium Tuberculosis

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Einar P. Wilder-Smith MD, DTM&H, FAMS (Neurology) Senior Consultant Associate Professor

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch71

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Wilder-Smith, E. P. (2009) Mycobacterium Tuberculosis, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch71

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • mycobacterium tuberculosis;
  • Tuberculosis (TB), as major health problem at the end of 1980s;
  • TB infection of nervous system - mainly affecting brain and spinal cord;
  • Tuberculous meningitis (TBM);
  • Tuberculosis of spine - termed Pott's disease;
  • Tuberculomas, consisting of Langerhans' cells, epitheloid cells and lymphocytes;
  • liquefication of caseous core of tuberculoma - resulting in formation of abscesses;
  • Tuberculous meningitis (TBM);
  • gadolinium-enhanced axial MRI using T1-weighted sequence


This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathophysiology

  • Clinical features

  • Investigations and diagnosis

  • Treatment

  • Further reading