Chapter 9. Coagulation Disorders in Stroke

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Kay Sin Tan MBBS (Melb), FRCP (Edin) Senior Lecturer

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch9

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Tan, K. S. (2009) Coagulation Disorders in Stroke, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch9

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Division of Neurology, Department of Medicine, University of Malaya Medical Centre, Kuala Lumpur, Malaysia

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • coagulation disorders in stroke;
  • hematological diseases - uncommon strokes causes;
  • hyperviscosity and sickle cell anemia - large arterial, watershed infarcts;
  • transcranial Doppler ultrasound - non-invasive Intracerebral arteriopathy monitoring;
  • prothrombotic disorders - inherited thrombophilias - antithrombin (AT) deficiency;
  • homocysteinemia - plasma homocysteine - ischemic stroke risk factor;
  • antiphospholipid antibodies and stroke - primary antiphospholipid syndrome (APLS);
  • APLS - recurrent migraine-like headaches and fetal loss;
  • thrombotic thrombocytopenic purpura (TTP) and ischemic strokes;
  • other coagulopathies - acquired hypercoagulopathy, in cancer patients


This chapter contains sections titled:

  • Introduction

  • Hyperviscosity

  • Prothrombotic disorders

  • Homocysteinemia

  • Antiphospholipid antibodies and stroke

  • Thrombotic thrombocytopenic purpura

  • Other coagulopathies

  • Further reading