Chapter 20. Cryoablation of Liver Tumors

  1. Pierre-Alain Clavien MD, Phd, FACS, FRCS Professor Chairman and
  2. Stefan Breitenstein MD
  1. Sivakumar Gananadha Senior lecturer1 and
  2. David L. Morris Professor of Surgery2

Published Online: 9 DEC 2009

DOI: 10.1002/9781444317053.ch20

Malignant Liver Tumors: Current and Emerging Therapies, Third Edition

Malignant Liver Tumors: Current and Emerging Therapies, Third Edition

How to Cite

Gananadha, S. and Morris, D. L. (2010) Cryoablation of Liver Tumors, in Malignant Liver Tumors: Current and Emerging Therapies, Third Edition (eds P.-A. Clavien and S. Breitenstein), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317053.ch20

Editor Information

  1. Department of Surgery, Swiss Hepato-Pancreato-Biliary and Transplantation Center, University Hospital Zurich, Zurich, Switzerland

Author Information

  1. 1

    Department of Surgery, The Canberra Hospital, Australian National University Medical School, Canberra, Australia

  2. 2

    UNSW Department of Surgery, St George Hospital, Sydney, NSW, Australia

Publication History

  1. Published Online: 9 DEC 2009
  2. Published Print: 12 JAN 2010

ISBN Information

Print ISBN: 9781405179768

Online ISBN: 9781444317053



  • Cryoablation of Liver Tumors;
  • magnetic resonance imaging (MRI);
  • Positron emission tomography (PET);
  • Prognostic factors after cryotherapy;
  • Colorectal liver metastases;
  • Minimally invasive approach;
  • carcinoembryonic antigen (CEA);
  • disseminated intravascular coagulation (DIC);
  • Neuroendocrine metastases


This chapter contains sections titled:

  • History

  • Mechanism of cryodestruction

  • Indications

  • Which ablative therapy?

  • Preoperative work-up

  • Equipment

  • Technique

  • Minimally invasive approach

  • Monitoring

  • Postoperative course and follow-up

  • Complications

  • Clinical results

  • Prognostic factors after cryotherapy

  • Combined modality therapies using cryoablation

  • Advantages and limitations

  • Self-assessment questions

  • References

  • Self-assessment answers