Chapter 34. Antiangiogenic Agents for Liver Tumors

  1. Pierre-Alain Clavien MD, Phd, FACS, FRCS Professor Chairman and
  2. Stefan Breitenstein MD
  1. Mathijs Vogten MD, PhD1,
  2. Emile E. Voest MD, PhD2 and
  3. Inne H. M. Borel Rinkes MD, PhD Professor of Surgery1

Published Online: 9 DEC 2009

DOI: 10.1002/9781444317053.ch34

Malignant Liver Tumors: Current and Emerging Therapies, Third Edition

Malignant Liver Tumors: Current and Emerging Therapies, Third Edition

How to Cite

Vogten, M., Voest, E. E. and Borel Rinkes, I. H. M. (2010) Antiangiogenic Agents for Liver Tumors, in Malignant Liver Tumors: Current and Emerging Therapies, Third Edition (eds P.-A. Clavien and S. Breitenstein), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317053.ch34

Editor Information

  1. Department of Surgery, Swiss Hepato-Pancreato-Biliary and Transplantation Center, University Hospital Zurich, Zurich, Switzerland

Author Information

  1. 1

    Department of Surgery University Medical Center Utrecht, The Netherlands

  2. 2

    Department of Medical Oncology, University Medical Center, Utrecht, The Netherlands

Publication History

  1. Published Online: 9 DEC 2009
  2. Published Print: 12 JAN 2010

ISBN Information

Print ISBN: 9781405179768

Online ISBN: 9781444317053

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Keywords:

  • Antiangiogenic Agents for Liver Tumors;
  • extracellular matrix (ECM);
  • Hepatocellular carcinoma (HCC);
  • Angiogenesis in liver tumors;
  • vascular endothelial growth factor (VEGF);
  • intravital microscopy (IVM);
  • Inhibition of angiogenic factors;
  • EGF receptor (EGFR);
  • extracellular signal - regulated kinase (ERK)

Summary

This chapter contains sections titled:

  • Angiogenesis: a new target for cancer therapy

  • Angiogenesis: vessel proliferation

  • Tumor growth is dependent on angiogenesis

  • Angiogenesis in liver tumors

  • Antiangiogenic agents

  • Future perspectives

  • Vascular targeting

  • Combination of antiangiogenic drugs with conventional treatment modalities

  • Self-assessment questions

  • References

  • Self-assessment answers