22. Urticaria and Mastocytosis

  1. Tony Burns MB, BS, FRCP Emeritus Consultant Dermatologist3,
  2. Stephen Breathnach MA, MB, BChir, MD, PhD, FRCP Consultant Dermatologist4,5,
  3. Neil Cox BSc, MB, ChB, FRCP(Lond & Edin) Consultant Dermatologist Visiting Professor6,7 and
  4. Christopher Griffiths BSc, MD, FRCP, FRCPath Professor of Dermatology Consultant Dermatologist8
  1. C. E. H. Grattan MA, MD, FRCP Consultant Dermatologist1 and
  2. A. Kobza Black MD, FRCP Honorary Senior Lecturer2

Published Online: 6 MAY 2010

DOI: 10.1002/9781444317633.ch22

Rook's Textbook of Dermatology, Eighth Edition

Rook's Textbook of Dermatology, Eighth Edition

How to Cite

Grattan, C. E. H. and Kobza Black, A. (2010) Urticaria and Mastocytosis, in Rook's Textbook of Dermatology, Eighth Edition (eds T. Burns, S. Breathnach, N. Cox and C. Griffiths), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317633.ch22

Editor Information

  1. 3

    Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, UK

  2. 4

    St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK

  3. 5

    Epsom & St Helier University Hospitals NHS Trust, Epsom, Surrey, UK

  4. 6

    Department of Dermatology, Cumberland Infirmary, Carlisle CA2 7HY, UK

  5. 7

    University of Cumbria, Carlisle CA1 2HH, UK

  6. 8

    The Dermatology Centre, University of Manchester, Salford Royal Hospital, Salford, Manchester M6 8HD, UK

Author Information

  1. 1

    Department of Dermatology, Norfolk and Norwich University Hospital, Colney Lane, Norwich NR4 7UY, UK

  2. 2

    St John's Institute of Dermatology, St Thomas' Hospital, London SE1 7EH, UK

Publication History

  1. Published Online: 6 MAY 2010
  2. Published Print: 22 MAR 2010

ISBN Information

Print ISBN: 9781405161695

Online ISBN: 9781444317633



  • urticaria and mastocytosis;
  • ordinary urticaria - common disease and different clinical presentations;
  • urticaria, recognized since days of Hippocrates;
  • mast cell mediators - urticaria due to local increase in capillary and venule permeability;
  • ordinary urticaria aetiology;
  • urticaria and mechanical forces;
  • idiopathic cold urticaria - immediate cold contact urticaria, the commonest form;
  • urticarial vasculitis, due to type III hypersensitivity immune reaction;
  • hereditary angio-oedema, a rare disorder;
  • mastocytosis, rare condition characterized by mast cells associated with altered immunophenotype


This chapter contains sections titled:

  • Urticaria

  • Ordinary urticaria

  • Physical and cholinergic urticarias [1,2]

  • Urticarial vasculitis [1-3]

  • Contact urticaria [1]

  • Angio-oedema (without weals) [1]

  • Other syndromes resembling urticaria or angio-oedema, or with urticaria as one component

  • Clinical history taking and diagnosis

  • Management

  • Mastocytosis

  • References