62. Systemic Disease and the Skin

  1. Tony Burns MB, BS, FRCP Emeritus Consultant Dermatologist2,
  2. Stephen Breathnach MA, MB, BChir, MD, PhD, FRCP Consultant Dermatologist3,4,
  3. Neil Cox BSc, MB, ChB, FRCP(Lond & Edin) Consultant Dermatologist Visiting Professor5,6 and
  4. Christopher Griffiths BSc, MD, FRCP, FRCPath Professor of Dermatology Consultant Dermatologist7
  1. N. H. Cox BSc, MB, ChB, FRCP(Lond & Edin) Consultant Dermatologist Visiting Professor5,6 and
  2. I. H. Coulson BSc, MB, BS, FRCP Consultant Dermatologist1

Published Online: 6 MAY 2010

DOI: 10.1002/9781444317633.ch62

Rook's Textbook of Dermatology, Eighth Edition

Rook's Textbook of Dermatology, Eighth Edition

How to Cite

Cox, N. H. and Coulson, I. H. (2010) Systemic Disease and the Skin, in Rook's Textbook of Dermatology, Eighth Edition (eds T. Burns, S. Breathnach, N. Cox and C. Griffiths), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317633.ch62

Editor Information

  1. 2

    Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, UK

  2. 3

    St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK

  3. 4

    Epsom & St Helier University Hospitals NHS Trust, Epsom, Surrey, UK

  4. 5

    Department of Dermatology, Cumberland Infirmary, Carlisle CA2 7HY, UK

  5. 6

    University of Cumbria, Carlisle CA1 2HH, UK

  6. 7

    The Dermatology Centre, University of Manchester, Salford Royal Hospital, Salford, Manchester M6 8HD, UK

Author Information

  1. 1

    Dermatology Unit, Burnley General Hospital, Casterton Avenue, Burnley BB10 2PQ, UK

  2. 5

    Department of Dermatology, Cumberland Infirmary, Carlisle CA2 7HY, UK

  3. 6

    University of Cumbria, Carlisle CA1 2HH, UK

Publication History

  1. Published Online: 6 MAY 2010
  2. Published Print: 22 MAR 2010

ISBN Information

Print ISBN: 9781405161695

Online ISBN: 9781444317633

SEARCH

Keywords:

  • systemic disease and skin;
  • pituitary syndromes - hyperpituitarism;
  • excessive secretion of growth hormone (GH, somatotrophin) - increase in plasma insulin-like growth factor-1 (IGF-1);
  • diffuse pigmentation in Nelson's syndrome;
  • hyperthyroidism - due to Graves' disease (diffuse toxic goitre, Basedow's disease);
  • diffuse alopecia and coarse hair due to hypothyroidism;
  • Acrokeratosis paraneoplastica (Bazex syndrome) - rare condition, commoner in males than females;
  • Mondor's disease, rare condition - cord-like lesion palpable in subcutaneous tissue of anterior or lateral thorax;
  • indirect cutaneous markers of internal malignancy;
  • skin pigment changes in liver disease

Summary

This chapter contains sections titled:

  • Endocrine disorders

  • Cutaneous markers of internal malignancy [1-11]

  • The gastrointestinal tract

  • Liver disease

  • Pancreatic disease

  • Renal disease [1-4]

  • Cardiac disease

  • Respiratory system

  • Haematology [1]

  • Graft-versus-host disease [1-5]

  • Bone and joint diseases

  • Annular and figurate reactive erythemas

  • References