Chapter 2. The Three Rs
- Robert Hubrecht,
- James Kirkwood
Published Online: 8 FEB 2010
DOI: 10.1002/9781444318777.ch2
Copyright © 2010 the Universities Federation for Animal Welfare
Book Title

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition
Additional Information
How to Cite
Richmond, J. (2010) The Three Rs, in The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition (eds R. Hubrecht and J. Kirkwood), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444318777.ch2
Editor Information
UFAW, The Old School, Brewhouse Hill, Wheathampstead, Hertfordshire AL4 8AN, UK
Publication History
- Published Online: 8 FEB 2010
- Published Print: 26 MAR 2010
Book Series:
ISBN Information
Print ISBN: 9781405175234
Online ISBN: 9781444318777
- Summary
- Chapter
- References
Keywords:
- Universities Federation for Animal Welfare (UFAW) - animals bred for experimental purposes;
- scientific approach to animal welfare - insights into ‘ what is meaningful to animals’;
- Three Rs (3Rs) - as part of mainstream science;
- animals used for scientific purposes - emotive and sensitive issues;
- high-fidelity fallacy;
- scientific validation and regulatory acceptance;
- replacement strategies and systems;
- refinement, improving quality of life - animals bred, kept for experimental purposes;
- animals in captivity, being dependent on man for their well-being;
- humane endpoints - direct welfare cost minimisation of justifiable animal-based research
Summary
This chapter contains sections titled:
Opening remarks
Introduction
Model systems
The Three Rs
Scientific validation and regulatory acceptance
Training and teamwork
Replacement
Reduction
Refinement
Humane endpoints
Responsibility for the Three Rs
Concluding remarks
References
