Chapter 2. The Three Rs

  1. Robert Hubrecht and
  2. James Kirkwood
  1. Jon Richmond

Published Online: 8 FEB 2010

DOI: 10.1002/9781444318777.ch2

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition

How to Cite

Richmond, J. (2010) The Three Rs, in The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition (eds R. Hubrecht and J. Kirkwood), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444318777.ch2

Editor Information

  1. UFAW, The Old School, Brewhouse Hill, Wheathampstead, Hertfordshire AL4 8AN, UK

Author Information

  1. Home Office, PO Box 6779, Dundee DD1 9WN, UK

Publication History

  1. Published Online: 8 FEB 2010
  2. Published Print: 26 MAR 2010

ISBN Information

Print ISBN: 9781405175234

Online ISBN: 9781444318777

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Keywords:

  • Universities Federation for Animal Welfare (UFAW) - animals bred for experimental purposes;
  • scientific approach to animal welfare - insights into ‘ what is meaningful to animals’;
  • Three Rs (3Rs) - as part of mainstream science;
  • animals used for scientific purposes - emotive and sensitive issues;
  • high-fidelity fallacy;
  • scientific validation and regulatory acceptance;
  • replacement strategies and systems;
  • refinement, improving quality of life - animals bred, kept for experimental purposes;
  • animals in captivity, being dependent on man for their well-being;
  • humane endpoints - direct welfare cost minimisation of justifiable animal-based research

Summary

This chapter contains sections titled:

  • Opening remarks

  • Introduction

  • Model systems

  • The Three Rs

  • Scientific validation and regulatory acceptance

  • Training and teamwork

  • Replacement

  • Reduction

  • Refinement

  • Humane endpoints

  • Responsibility for the Three Rs

  • Concluding remarks

  • References