Chapter 21. The Laboratory Mouse

  1. Robert Hubrecht and
  2. James Kirkwood
  1. Vera Baumans

Published Online: 8 FEB 2010

DOI: 10.1002/9781444318777.ch21

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition

How to Cite

Baumans, V. (2010) The Laboratory Mouse, in The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition (eds R. Hubrecht and J. Kirkwood), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444318777.ch21

Editor Information

  1. UFAW, The Old School, Brewhouse Hill, Wheathampstead, Hertfordshire AL4 8AN, UK

Author Information

  1. Department Animals in Science and Society, Division Laboratory Animal Science, Utrecht University, PO Box 80.166, 3508 TD Utrecht, The Netherlands

Publication History

  1. Published Online: 8 FEB 2010
  2. Published Print: 26 MAR 2010

ISBN Information

Print ISBN: 9781405175234

Online ISBN: 9781444318777

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Keywords:

  • laboratory mouse and interest in Mendelian genetics;
  • mice as social animals, living in compatible, single male dominated groups;
  • standard biological data environmental requirements and physiological parameters of mice;
  • inbred mice - studied for immunology, oncology, microbiology, biochemistry, pharmacology, physiology, anatomy and radiobiology;
  • mouse, vertebrate species in biomedical research;
  • genetically engineered or modified mice - those with induced mutations;
  • identification and sexing;
  • laboratory animals, classified according to microbiological status (conventional, specific pathogen free (SPF) or gnotobiotic);
  • humane endpoint determination - humane killing of animals, signs of approaching death;
  • well-being of animals and homeostasis - imbalance manifesting as disease or abnormal behaviours

Summary

This chapter contains sections titled:

  • Biological overview

  • Uses in the laboratory

  • Laboratory management and breeding

  • Sources of supply

  • Feeding

  • Water

  • Laboratory procedures

  • Common welfare problems

  • Euthanasia

  • Acknowledgement

  • Further reading

  • References