Chapter 3. The Design of Animal Experiments
- Robert Hubrecht,
- James Kirkwood
Published Online: 8 FEB 2010
DOI: 10.1002/9781444318777.ch3
Copyright © 2010 the Universities Federation for Animal Welfare
Book Title
The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition
Additional Information
How to Cite
Festing, M. F. W. (2010) The Design of Animal Experiments, in The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals, Eighth Edition (eds R. Hubrecht and J. Kirkwood), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444318777.ch3
Editor Information
UFAW, The Old School, Brewhouse Hill, Wheathampstead, Hertfordshire AL4 8AN, UK
Publication History
- Published Online: 8 FEB 2010
- Published Print: 26 MAR 2010
Book Series:
ISBN Information
Print ISBN: 9781405175234
Online ISBN: 9781444318777
- Summary
- Chapter
- References
Keywords:
- design of animal experiments;
- research workers, animal house staff and ethical review committee members;
- research strategy and models in research;
- pilot experiments - exploratory experiments and confirmatory experiments;
- optimum group size - size of differences, group means and inter-individual variability;
- dependent and independent variables - variables in experiments;
- randomised controlled, double-blinded clinical trial - gold standard for design;
- measurement error and variability in procedures;
- analysis of variance and t-test - comparing means of two;
- factorial experimental designs
Summary
This chapter contains sections titled:
Introduction
Research strategy and the use of models in research
Steps in the design of an experiment
Statistical analysis of planned experiments
Some experimental designs
Concluding remarks
References