Chapter 16. Genes, Genetics, Genomics and Epigenetics

  1. Peter G. Miller2,
  2. John Strang3,4 and
  3. Peter M. Miller5
  1. David Ball1,4 and
  2. Irene Guerrini4

Published Online: 16 FEB 2010

DOI: 10.1002/9781444318852.ch16

Addiction Research Methods

Addiction Research Methods

How to Cite

Ball, D. and Guerrini, I. (2010) Genes, Genetics, Genomics and Epigenetics, in Addiction Research Methods (eds P. G. Miller, J. Strang and P. M. Miller), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444318852.ch16

Editor Information

  1. 2

    School of Psychology, Deakin University, Victoria, Australia

  2. 3

    National Addiction Centre Institute of Psychiatry, Kings College London, UK

  3. 4

    South London and Maudsley NHS Foundation Trust, London, UK

  4. 5

    Center for Drug and Alcohol Programs, Medical University & South Carolina, Charleston, SC, USA

Author Information

  1. 1

    Social Genetic and Developmental Psychiatry Centre, King's College London, UK

  2. 4

    South London and Maudsley NHS Foundation Trust, London, UK

Publication History

  1. Published Online: 16 FEB 2010
  2. Published Print: 2 APR 2010

ISBN Information

Print ISBN: 9781405176637

Online ISBN: 9781444318852



  • genes, genetics, genomics and epigenetics;
  • Gregor Johann Mendel Gregor Mendel, Augustian monk - ‘father of modern genetics’;
  • DNA double helix;
  • animal models, in dissecting complex, multifactorial traits;
  • Recombinant inbred (RI) strains, derived from standard inbred strains homozygous at all genetic loci;
  • quantitative genetics;
  • quantitative genetics, tool exploring a common disorder aggregating in families;
  • family study approach – principle, a disease or a trait has a genetic component;
  • segregation analysis, evaluating contributions of genes to expression of phenotype


This chapter contains sections titled:

  • Introduction

  • Animal studies

  • Quantitative genetics

  • Molecular genetics

  • Why bother?

  • An addiction gene

  • Ethics

  • Concluding remarks

  • References