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Chapter 4. Experimental Design Issues in Addiction Research

  1. Peter G. Miller2,
  2. John Strang3,4 and
  3. Peter M. Miller5
  1. Robert West

Published Online: 16 FEB 2010

DOI: 10.1002/9781444318852.ch4

Addiction Research Methods

Addiction Research Methods

How to Cite

West, R. (2010) Experimental Design Issues in Addiction Research, in Addiction Research Methods (eds P. G. Miller, J. Strang and P. M. Miller), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444318852.ch4

Editor Information

  1. 2

    School of Psychology, Deakin University, Victoria, Australia

  2. 3

    National Addiction Centre Institute of Psychiatry, Kings College London, UK

  3. 4

    South London and Maudsley NHS Foundation Trust, London, UK

  4. 5

    Center for Drug and Alcohol Programs, Medical University & South Carolina, Charleston, SC, USA

Author Information

  1. Department of Epidemiology and Public Health, University College London, London, UK

Publication History

  1. Published Online: 16 FEB 2010
  2. Published Print: 2 APR 2010

ISBN Information

Print ISBN: 9781405176637

Online ISBN: 9781444318852



  • experimental design issues in addiction research;
  • design options available;
  • cluster-randomised between-group designs;
  • stepped wedge design - possibility of evaluating interventions experimentally;
  • preference designs and randomised consent designs;
  • N-of-1 designs;
  • question of what intervention and comparison conditions to adopt;
  • ‘nicotine replacement therapy’ (NRT);
  • target population and recruitment strategy;
  • making the wrong choice of experimental procedure - fatal for a study


This chapter contains sections titled:

  • Introduction

  • What constitutes an experiment?

  • Is an experiment appropriate?

  • What kind of experimental design?

  • What intervention and comparison conditions?

  • What target population and recruitment strategy?

  • What sample size?

  • What outcome measures?

  • What statistical analyses?

  • Conclusions

  • References

  • Recommended readings