Chapter 2. Introduction to Mutant Pigmentary Genes

  1. M. Lynn Lamoreux1,
  2. Véronique Delmas2,
  3. Lionel Larue2 and
  4. Dorothy C. Bennett3

Published Online: 6 MAY 2010

DOI: 10.1002/9781444319651.ch2

The Colors of Mice: A Model Genetic Network

The Colors of Mice: A Model Genetic Network

How to Cite

Lamoreux, M. L., Delmas, V., Larue, L. and Bennett, D. C. (2010) Introduction to Mutant Pigmentary Genes, in The Colors of Mice: A Model Genetic Network, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444319651.ch2

Author Information

  1. 1

    Bryan, Texas, USA

  2. 2

    Developmental Genetics of Melanocytes, Institut Curie, Orsay, France

  3. 3

    Molecular and Metabolic Signalling Centre, St. George's, University of London, UK

Publication History

  1. Published Online: 6 MAY 2010
  2. Published Print: 16 APR 2010

ISBN Information

Print ISBN: 9781405179546

Online ISBN: 9781444319651

SEARCH

Keywords:

  • introduction to mutant pigmentary genes;
  • normal melanocyte development defects - white spotting and graying with age;
  • defects in normal melanosome development - albinism;
  • melanosomes transport to other cells - ‘dilute’ phenotype;
  • pigment-type switching - eumelanogenesis to pheomelanogenesis;
  • ‘eumelanin/pheomelanin switch mechanism’ - complex control over pigment patterning

Summary

This chapter contains sections titled:

  • Defects of normal melanocyte development: white spotting and graying with age

  • Defects in normal melanosome development: albinism

  • Transport of melanosomes to other cells: the ‘dilute’ phenotype

  • Pigment-type switching: from eumelanogenesis to pheomelanogenesis