Chapter 5. Pigment-Type Switching

  1. M. Lynn Lamoreux1,
  2. Véronique Delmas2,
  3. Lionel Larue2 and
  4. Dorothy C. Bennett3

Published Online: 6 MAY 2010

DOI: 10.1002/9781444319651.ch5

The Colors of Mice: A Model Genetic Network

The Colors of Mice: A Model Genetic Network

How to Cite

Lamoreux, M. L., Delmas, V., Larue, L. and Bennett, D. C. (2010) Pigment-Type Switching, in The Colors of Mice: A Model Genetic Network, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444319651.ch5

Author Information

  1. 1

    Bryan, Texas, USA

  2. 2

    Developmental Genetics of Melanocytes, Institut Curie, Orsay, France

  3. 3

    Molecular and Metabolic Signalling Centre, St. George's, University of London, UK

Publication History

  1. Published Online: 6 MAY 2010
  2. Published Print: 16 APR 2010

ISBN Information

Print ISBN: 9781405179546

Online ISBN: 9781444319651



  • pigment-type switching;
  • eumelanin/pheomelanin switch - genetic control over organelle, cell, and tissue biology;
  • yellow phenotypes, MC1R complex - pigment production type;
  • eumelanin/pheomelanin distribution chimeric pattern - keratinocytes chimerism;
  • melanin pigment - pheomelanin chemically compared with eumelanin;
  • melanogenesis - eumelanin/pheomelanin switch mechanism;
  • signaling cellular level switch mechanism;
  • yellow genes - recessive yellow locus encodes MC1R


This chapter contains sections titled:

  • Introduction

  • Yellow phenotypes

  • Melanin pigment

  • Melanogenesis and the eumelanin/pheomelanin switch mechanism

  • Signaling the switch mechanism at the cellular level

  • Yellow genes