Chapter 6. Novel Mouse Pigmentary Mutants Generated by Genetic Manipulation

  1. M. Lynn Lamoreux1,
  2. Véronique Delmas2,
  3. Lionel Larue2 and
  4. Dorothy C. Bennett3

Published Online: 6 MAY 2010

DOI: 10.1002/9781444319651.ch6

The Colors of Mice: A Model Genetic Network

The Colors of Mice: A Model Genetic Network

How to Cite

Lamoreux, M. L., Delmas, V., Larue, L. and Bennett, D. C. (2010) Novel Mouse Pigmentary Mutants Generated by Genetic Manipulation, in The Colors of Mice: A Model Genetic Network, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444319651.ch6

Author Information

  1. 1

    Bryan, Texas, USA

  2. 2

    Developmental Genetics of Melanocytes, Institut Curie, Orsay, France

  3. 3

    Molecular and Metabolic Signalling Centre, St. George's, University of London, UK

Publication History

  1. Published Online: 6 MAY 2010
  2. Published Print: 16 APR 2010

ISBN Information

Print ISBN: 9781405179546

Online ISBN: 9781444319651

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Keywords:

  • technology and resources;
  • novel mouse pigmentary mutants generated by genetic manipulation;
  • mouse transgenesis - genetically engineered mice generation;
  • coat-color transgenic mice - generation by microinjection of cDNA;
  • coat-color mutants generated by gene targeting;
  • genetic background influence - generating and analyzing mouse mutations

Summary

This chapter contains sections titled:

  • Introduction

  • Mouse transgenesis: generation of genetically engineered mice

  • Coat-color transgenic mice

  • The coat-color mutants generated by gene targeting

  • Influence of the genetic background

  • Conclusions