Chapter 26. Current Concepts in Bone Biology

  1. Clark Spencer Larsen Distinguished Professor Chair Fellow Chair-Elect vice president
  1. James H. Gosman Adjunct Professor member and
  2. Samuel D. Stout Professor Fellow

Published Online: 3 MAR 2010

DOI: 10.1002/9781444320039.ch26

A Companion to Biological Anthropology

A Companion to Biological Anthropology

How to Cite

Gosman, J. H. and Stout, S. D. (2010) Current Concepts in Bone Biology, in A Companion to Biological Anthropology (ed C. S. Larsen), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444320039.ch26

Editor Information

  1. The Ohio State University, USA

Author Information

  1. The Ohio State University, USA

Publication History

  1. Published Online: 3 MAR 2010
  2. Published Print: 2 APR 2010

ISBN Information

Print ISBN: 9781405189002

Online ISBN: 9781444320039

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Keywords:

  • current concepts in bone biology;
  • physical anthropology seeking to understand biological aspects of human and non-human primates, past and present;
  • basic multicellular units of remodeling (BMUs);
  • interrelationship between biology and mechanical environment - foundation of mechanobiology;
  • bone strain, mediated through cellular responses of osteoblast and osteoclast lineages;
  • bone-lining cells (BLC) - quiescent osteoblasts escaped being buried by newly formed bone;
  • bone remodeling - three apparent purposes;
  • developments in bone remodeling theory;
  • unified trabecular/cortical bone paradigm;
  • age-associated bone loss, among human populations, past and present

Summary

This chapter contains sections titled:

  • Introduction

  • Mechanobiology

  • Cellular Actors

  • (RE-)Modeling

  • Developments in Bone Remodeling Theory

  • Ontogenic Patterns and Mechanical Loading

  • Bone Gain/Loss

  • Conclusions

  • References