Chapter 3. Epidemiology of Type 1 Diabetes

  1. Richard I. G. Holt MA, MB BChir, PhD, FRCP, FHEA Professor in Diabetes & Endocrinology7,
  2. Clive S. Cockram MB BS, BSc, MD (Lond), FRCP, FRACP, FHKAM (Med) Emeritus Professor of Medicine8,
  3. Allan Flyvbjerg MD, DMSc Professor of Clinical Endocrinology Chair9 and
  4. Barry J. Goldstein MD, PhD, FACP, FACE Therapeutic Area Head Vice President10
  1. Lars C. Stene1,2,
  2. Valma Harjutsalo PhD3,4,5,
  3. Elena Moltchanova PhD3 and
  4. Jaakko Tuomilehto3,6

Published Online: 9 JUL 2010

DOI: 10.1002/9781444324808.ch3

Textbook of Diabetes, Fourth Edition

Textbook of Diabetes, Fourth Edition

How to Cite

Stene, L. C., Harjutsalo, V., Moltchanova, E. and Tuomilehto, J. (2010) Epidemiology of Type 1 Diabetes, in Textbook of Diabetes, Fourth Edition (eds R. I. G. Holt, C. S. Cockram, A. Flyvbjerg and B. J. Goldstein), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444324808.ch3

Editor Information

  1. 7

    Developmental Origins of Health and Disease Division, University of Southampton School of Medicine, Southampton, UK

  2. 8

    Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China

  3. 9

    Department of Endocrinology and Internal Medicine, The Medical Research Laboratories, Aarhus University Hospital – Aarhus University, Aarhus, Denmark

  4. 10

    Clinical Research, Metabolism Merck Research Laboratories Rahway, NJ, USA

Author Information

  1. 1

    Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway

  2. 2

    Oslo Diabetes Research Centre, Oslo University Hospital, Oslo, Norway

  3. 3

    Diabetes Prevention Unit, Department of Health Promotion, National Institute of Health and Welfare, Helsinki, Finland

  4. 4

    Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, Finland

  5. 5

    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland

  6. 6

    Department of Public Health, University of Helsinki, Helsinki, Finland

Publication History

  1. Published Online: 9 JUL 2010
  2. Published Print: 9 JUL 2010

ISBN Information

Print ISBN: 9781405191814

Online ISBN: 9781444324808



  • Type 1 diabetes mellitus (T1DM);
  • glutamine acid decarboxylase (GAD);
  • human leukocyte antigen (HLA);
  • The World Health Organization (WHO);
  • Congenital rubella syndrome (CRS)


This chapter contains sections titled:

  • Introduction

  • Occurrence of T1DM by age, sex, place and time

  • Familial clustering and twin studies

  • Environmental risk factors for T1DM: clues from epidemiologic studies

  • Mortality

  • Conclusions

  • Acknowledgment

  • References