7. Pharmacokinetic Principles of Antiepileptic Drug Treatment

  1. Simon Shorvon MA, MB BChir, MD, FRCP Professor of Neurology Clinical Subdean Consultant Neurologist1,2

Published Online: 16 MAR 2011

DOI: 10.1002/9781444325201.ch7

Handbook of Epilepsy Treatment, Third Edition

Handbook of Epilepsy Treatment, Third Edition

How to Cite

Shorvon, S. (2010) Pharmacokinetic Principles of Antiepileptic Drug Treatment, in Handbook of Epilepsy Treatment, Third Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444325201.ch7

Author Information

  1. 1

    UCL Institute of Neurology, University College London, UK

  2. 2

    National Hospital for Neurology and Neurosurgery, Queen Square London, UK

Publication History

  1. Published Online: 16 MAR 2011
  2. Published Print: 21 NOV 2010

ISBN Information

Print ISBN: 9781405198189

Online ISBN: 9781444325201

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Keywords:

  • Pharmacokinetic Principles of Antiepileptic Drug Treatment;
  • Drug distribution;
  • Buccal and intranasal administration and inhalation;
  • Drug transport systems across the blood-brain barrier-‘drug resistance’ proteins;
  • Drug elimination (metabolism and excretion);
  • Blood level measurements;
  • ‘treating the patient, not the serum level’

Summary

This chapter contains sections titled:

  • Drug absorption

  • Drug distribution

  • Drug elimination (metabolism and excretion)

  • Blood level measurements