Chapter 38. Preparative and Industrial-Scale Isolation and Purification of Omega-3 Polyunsaturated Fatty Acids from Marine Sources

  1. Associate Professor Cesarettin Alasalvar1,
  2. Professor Fereidoon Shahidi2,
  3. Professor Kazuo Miyashita3 and
  4. Dr Udaya Wanasundara4
  1. Dr Udaya Wanasundara

Published Online: 2 SEP 2010

DOI: 10.1002/9781444325546.ch38

Handbook of Seafood Quality, Safety and Health Applications

Handbook of Seafood Quality, Safety and Health Applications

How to Cite

Wanasundara, U. (2010) Preparative and Industrial-Scale Isolation and Purification of Omega-3 Polyunsaturated Fatty Acids from Marine Sources, in Handbook of Seafood Quality, Safety and Health Applications (eds C. Alasalvar, F. Shahidi, K. Miyashita and U. Wanasundara), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444325546.ch38

Editor Information

  1. 1

    TÜBİTAK Marmara Research Centre, Food Institute, Gebze/Kocaeli, Turkey

  2. 2

    Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL, Canada

  3. 3

    Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Japan

  4. 4

    POS Pilot Plant Corporation, Saskatoon, SK, Canada

Author Information

  1. POS Pilot Plant Corporation, Saskatoon, SK, Canada

Publication History

  1. Published Online: 2 SEP 2010
  2. Published Print: 1 OCT 2010

ISBN Information

Print ISBN: 9781405180702

Online ISBN: 9781444325546

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Keywords:

  • preparative and industrial-scale isolation - and purification of omega-3 polyunsaturated fatty acids from marine sources;
  • long-chain omega-3 polyunsaturated fatty acids (PUFA) - importance among scientific community;
  • beneficial effects of n-3 PUFA - their ability to lower serum triacylglycerols (TAG);
  • concentration methods of n-3 PUFA;
  • gas chromatographic separation methods - for analytical purposes;
  • counter-current chromatography (CCC) and/or centrifugal partition chromatography (CPC) - for isolation of PUFA;
  • supercritical fluid extraction (SFE), relatively new separation process - circumventing problems of conventional separation techniques;
  • low-temperature crystallization method;
  • enriching n-3 PUFA content - in acylglycerols using microbial lipases;
  • TAG form of PUFA, nutritionally more favourable - than methyl or ethyl esters of fatty acids

Summary

This chapter contains sections titled:

  • Introduction

  • Concentration methods of n-3 PUFA

  • Conclusions

  • References