3. Child and Adolescent Schizophrenia

  1. Daniel R. Weinberger MD3 and
  2. Paul J. Harrison MA, BM, BCh, DM(Oxon), FRCPsych4
  1. Chris Hollis MBBS, BSc, PhD, DCH, MRCPsych1 and
  2. Judith Rapoport2

Published Online: 8 MAR 2011

DOI: 10.1002/9781444327298.ch3

Schizophrenia, Third Edition

Schizophrenia, Third Edition

How to Cite

Hollis, C. and Rapoport, J. (2010) Child and Adolescent Schizophrenia, in Schizophrenia, Third Edition (eds D. R. Weinberger and P. J. Harrison), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444327298.ch3

Editor Information

  1. 3

    Genes, Cognition and Psychosis Program, Clinical Studies Section, Clinical Brain Disorders Branch, National Institute of Health, Bethesda, MD, USA

  2. 4

    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK

Author Information

  1. 1

    Division of Psychiatry, University of Nottingham, Queen's Medical Centre, Nottingham, UK

  2. 2

    National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA

Publication History

  1. Published Online: 8 MAR 2011
  2. Published Print: 10 DEC 2010

ISBN Information

Print ISBN: 9781405176972

Online ISBN: 9781444327298



  • child-;
  • childhood-;
  • adolescent-;
  • schizophrenia;
  • neurodevelopment;
  • brain development;
  • psychosis;
  • diagnosis;
  • treatment


Schizophrenia in childhood and adolescence appears clinically and biologically continuous with the adult-onset disorder. The most striking differences appear to be the greater clinical severity and more frequent and more pronounced early neurodevelopment abnormalities. It is likely that there are progressive brain changes before and during illness. It is imperative that clinicians dealing with this age group are better trained to address the many educational, family, and medical needs of these patients.