10. Induction Therapy of Acute Myeloid Leukemia

  1. Stefan Faderl MD Associate Professor and
  2. Hagop Kantarjian MD Chairman Professor
  1. Martha Wadleigh MD Assistant Professor of Medicine1 and
  2. Daniel J. Deangelo MD, PhD Associate Professor of Medicine Clinical Director2

Published Online: 4 JAN 2011

DOI: 10.1002/9781444327359.ch10

Leukemias: Principles and Practice of Therapy

Leukemias: Principles and Practice of Therapy

How to Cite

Wadleigh, M. and Deangelo, D. J. (2010) Induction Therapy of Acute Myeloid Leukemia, in Leukemias: Principles and Practice of Therapy (eds S. Faderl and H. Kantarjian), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444327359.ch10

Editor Information

  1. Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX, USA

Author Information

  1. 1

    Harvard Medical School, Department of Medical Oncology, Dana - Farber Cancer Institute, Boston, Massachusetts, USA

  2. 2

    Harvard Medical School, Adult Leukemia Program, Department of Medical Oncology, Dana - Farber Cancer Institute, Boston, Massachusetts, USA

Publication History

  1. Published Online: 4 JAN 2011
  2. Published Print: 26 NOV 2010

ISBN Information

Print ISBN: 9781405182355

Online ISBN: 9781444327359

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Keywords:

  • Acute myeloid leukemia (AML);
  • activated partial thromboplastin time (aPTT);
  • lactate dehydrogenase (LDH);
  • herpes simplex virus (HSV);
  • Human leukocyte antigen (HLA);
  • central nervous system (CNS);
  • cerebrospinal fluid (CSF);
  • Cancer and Leukemia Group B (CALGB);
  • Eastern Cooperative Oncology Group (ECOG);
  • Acute Leukemia French Association (ALFA)

Summary

This chapter contains sections titled:

  • Pre-treatment evaluation

  • Choice of anthracycline

  • Dose of anthracycline

  • Dose of cytarabine

  • Double induction and timed-sequential therapy

  • Addition of other agents to standard therapy

  • Priming and growth-factor support

  • Monoclonal antibodies

  • Alternative strategies

  • FLT3 inhibitors

  • Conclusion

  • References