19. Acute Lymphoblastic Leukemia in Adolescents and Young Adults

  1. Stefan Faderl MD Associate Professor and
  2. Hagop Kantarjian MD Chairman Professor
  1. Michael E. Rytting MD

Published Online: 4 JAN 2011

DOI: 10.1002/9781444327359.ch19

Leukemias: Principles and Practice of Therapy

Leukemias: Principles and Practice of Therapy

How to Cite

Rytting, M. E. (2010) Acute Lymphoblastic Leukemia in Adolescents and Young Adults, in Leukemias: Principles and Practice of Therapy (eds S. Faderl and H. Kantarjian), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444327359.ch19

Editor Information

  1. Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX, USA

Author Information

  1. M. D. Anderson Cancer Center, Houston, Texas, USA

Publication History

  1. Published Online: 4 JAN 2011
  2. Published Print: 26 NOV 2010

ISBN Information

Print ISBN: 9781405182355

Online ISBN: 9781444327359

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Keywords:

  • acute lymphoblastic leukemia (ALL);
  • pediatric and adult chemotherapy for ALL;
  • radiation therapy;
  • bone marrow transplant

Summary

The therapy of acute lymphoblastic leukemia (ALL) in the adolescent and young adult patient presents several challenges. Clinicians who care for these patients need to be familiar with both pediatric and adult chemotherapy regimens for ALL. Based on experience in treating older adolescents, pediatric treatment regimens are being investigated in this age group, and early indications are that these regimens are feasible and effective. The role of radiation therapy and bone marrow transplant in this group of patients is being further defined. Owing to their unique position between pediatric and adult practices, these patients afford an opportunity for cooperation between adult and pediatric oncologists and for advancement of leukemia therapy in general.