Chapter 2. Normally Occurring Environmental and Behavioral Influences on Gene Activity

From Central Dogma to Probabilistic Epigenesis

  1. Kathryn E. Hood1,
  2. Carolyn Tucker Halpern2,
  3. Gary Greenberg3 and
  4. Richard M. Lerner4
  1. Gilbert Gottlieb

Published Online: 13 AUG 2010

DOI: 10.1002/9781444327632.ch2

Handbook of Developmental Science, Behavior, and Genetics

Handbook of Developmental Science, Behavior, and Genetics

How to Cite

Gottlieb, G. (2010) Normally Occurring Environmental and Behavioral Influences on Gene Activity, in Handbook of Developmental Science, Behavior, and Genetics (eds K. E. Hood, C. T. Halpern, G. Greenberg and R. M. Lerner), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444327632.ch2

Editor Information

  1. 1

    The Pennsylvania State University, USA

  2. 2

    University of North Carolina at Chapel Hill, USA

  3. 3

    Wichita State University, USA

  4. 4

    Tufts University, USA

Publication History

  1. Published Online: 13 AUG 2010
  2. Published Print: 13 SEP 2010

ISBN Information

Print ISBN: 9781405187824

Online ISBN: 9781444327632

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Keywords:

  • normally occurring environmental and behavioral influences on gene activity - central dogma to probabilistic epigenesis;
  • dichotomous view, that genes and endogenous factors - as construct part of organism;
  • epigenetic development concepts - predetermined and probabilistic epigenesis;
  • predetermined epigenesis - unidirectional structure—function development;
  • central dogma, “information” flowing in one direction - from genes to structure of proteins;
  • genes and neurons in brains of organisms - in different lineages;
  • different naturally occurring environmental signals - stimulating gene expression in organisms, nematodes to humans;
  • from central dogma of molecular biology - to probabilistic epigenesis;
  • genetic activity, according to probabilistic epigenesis;
  • normally occurring environmental influences on gene activity - not raising spectre of a new, subtle form of “environmentalism”

Summary

This chapter contains sections titled:

  • Predetermined and Probabilistic Epigenesis

  • The Central Dogma

  • The Genome According to Central Dogma

  • Normally Occurring Environmental Influences on Gene Activity

  • From Central Dogma of Molecular Biology to Probabilistic Epigenesis

  • Importance of Behavioral and Neural Activity in Determining Gene Expression, Anatomical Structure, and Physiological Function

  • Summary and Conclusions

  • References