2. Molecular Aspects of Nutrition

  1. Dr Susan A Lanham-New2,
  2. Professor Ian A Macdonald3 and
  3. Associate Professor Helen M Roche4
  1. Associate Professor Helen M Roche4,
  2. Assistant Professor Herman E Popeijus1 and
  3. Professor Ronald P Mensink1

Published Online: 16 MAR 2011

DOI: 10.1002/9781444327779.ch2

Nutrition and Metabolism, Second Edition

Nutrition and Metabolism, Second Edition

How to Cite

Roche, H. M., Popeijus, H. E. and Mensink, R. P. (2010) Molecular Aspects of Nutrition, in Nutrition and Metabolism, Second Edition (eds S. A. Lanham-New, I. A. Macdonald and H. M. Roche), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444327779.ch2

Editor Information

  1. 2

    University of Surrey, UK

  2. 3

    University of Nottingham, UK

  3. 4

    University College Dublin, Ireland

Author Information

  1. 1

    Maastricht University, The Netherlands

  2. 4

    University College Dublin, Ireland

Publication History

  1. Published Online: 16 MAR 2011
  2. Published Print: 19 NOV 2010

ISBN Information

Print ISBN: 9781405168083

Online ISBN: 9781444327779



  • molecular aspects of nutrition;
  • genome, information or blueprint - and full complement of genes;
  • genes, characteristics of life - gender, physical characteristics, metabolic functions and life stage;
  • molecular nutrition, relationship between - human genome and nutrition;
  • molecular biology core concepts - genome, DNA and genetic code;
  • genetic polymorphisms - forms of same allele in population;
  • DNA damage, genetic mutations and heritability - monogenic and polygenic disorders;
  • gene expression - transcription and translation;
  • animal studies, nutrient effects - in animals, similar genetic background;
  • single-gene expression - and mRNA transcript quantification of specific gene


This chapter contains sections titled:

  • Introduction

  • Core concepts in molecular biology

  • Gene expression: transcription and translation

  • Research tools to investigate molecular aspects of nutrition

  • Genetic variability: determinants of health and response to nutrients

  • Nutrient regulation of gene expression

  • Perspectives on the future

  • Reference

  • Further reading