8. Nutrition and the Brain

  1. Dr Susan A Lanham-New2,
  2. Professor Ian A Macdonald3 and
  3. Associate Professor Helen M Roche4
  1. Professor John D Fernstrom and
  2. Dr Madelyn H Fernstrom

Published Online: 16 MAR 2011

DOI: 10.1002/9781444327779.ch8

Nutrition and Metabolism, Second Edition

Nutrition and Metabolism, Second Edition

How to Cite

Fernstrom, J. D. and Fernstrom, M. H. (2010) Nutrition and the Brain, in Nutrition and Metabolism, Second Edition (eds S. A. Lanham-New, I. A. Macdonald and H. M. Roche), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444327779.ch8

Editor Information

  1. 2

    University of Surrey, UK

  2. 3

    University of Nottingham, UK

  3. 4

    University College Dublin, Ireland

Author Information

  1. University of Pittsburgh, USA

Publication History

  1. Published Online: 16 MAR 2011
  2. Published Print: 19 NOV 2010

ISBN Information

Print ISBN: 9781405168083

Online ISBN: 9781444327779



  • nutrition and the brain;
  • brain chemistry and function - by short- and long-term changes in diet;
  • glucose, principal energy substrate of brain - ketone bodies, energy substrates during starvation;
  • true nature of blood–brain barrier (BBB) - a very old concept;
  • BBB, central to any consideration - how food affects the brain;
  • brain, and glucose - as its primary energy substrate;
  • neuronal and glial cells in brain use - amino acids producing proteins;
  • dietary intake of carbohydrates - not influencing glucose availability to brain;
  • Vitamin E, antioxidant and free radical scavenger - fatty acid protection in cellular membranes;
  • copper deficiency, as X-linked genetic disease - copper transport in Menkes disease


This chapter contains sections titled:

  • Introduction

  • General organisation of the mammalian nervous system

  • The blood–brain barrier

  • Energy substrates

  • Amino acids and protein

  • Vitamins and minerals

  • Perspectives on the future

  • Further reading