Chapter 17. Management of Amyotrophic Lateral Sclerosis

  1. Nils Erik Gilhus MD, PhD Professor14,
  2. Michael P. Barnes MD, FRCP Professor of Neurological Rehabilitation Medical Director15 and
  3. Michael Brainin MD Professor16
  1. P. M. Andersen (chairman)1,
  2. S. Abrahams2,
  3. G. D. Borasio3,
  4. M. de Carvalho4,
  5. A. Chio5,
  6. P. Van Damme6,
  7. O. Hardiman7,
  8. K. Kollewe8,
  9. K. E. Morrison9,
  10. S. Petri8,
  11. P. -F. Pradat10,
  12. V. Silani11,
  13. B. Tomik12,
  14. M. Wasner3 and
  15. M. Weber13

Published Online: 6 SEP 2010

DOI: 10.1002/9781444328394.ch17

European Handbook of Neurological Management, Second Edition, Volume 1, Second Edition

European Handbook of Neurological Management, Second Edition, Volume 1, Second Edition

How to Cite

Gilhus, N. E., Barnes, M. P. and Brainin, M. (2010) Management of Amyotrophic Lateral Sclerosis, in European Handbook of Neurological Management, Second Edition, Volume 1, Second Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444328394.ch17

Author Information

  1. 14

    Department of Clinical Medicine, University of Bergen and Department of Neurology, Haukeland University Hospital, Bergen, Norway

  2. 15

    University of Newcastle, Hunters Moor Neurorehabilitation Ltd, Newcastle upon Tyne, UK

  3. 16

    Department of Clinical Medicine and Prevention, and Center for Clinical Neurosciences, Donau-Universität Krems, Department of Neurology, Landesklinikum Donauregion Tulln Tulln, Austria

Author Information

  1. 1

    Umeå University Hospital, Sweden

  2. 2

    University of Edinburgh, UK

  3. 3

    Munich University Hospital, Germany

  4. 4

    Hospital de Santa Maria, Lisbon, Portugal

  5. 5

    University of Turin and San Giovanni Hospital, Turin, Italy

  6. 6

    University of Leuven, Belgium

  7. 7

    Trinity College and Beaumont Hospital, Dublin, Ireland

  8. 8

    Medizinische Hochschule Hannover, Germany

  9. 9

    Queen Elizabeth Hospital and School of Clinical and Experimental Medicine, University of Birmingham, UK

  10. 10

    Hôpital de la Salpêtrière, Paris, France

  11. 11

    University of Milan Medical School, Italy

  12. 12

    Jagiellonian University Medical College, Krakow, Poland

  13. 13

    Kantonsspital St. Gallen, Switzerland

Publication History

  1. Published Online: 6 SEP 2010
  2. Published Print: 15 OCT 2010

ISBN Information

Print ISBN: 9781405185332

Online ISBN: 9781444328394



  • neuromuscular diseases - management of amyotrophic lateral sclerosis;
  • amyotrophic lateral sclerosis (ALS) - motor neuron disease or MND, characterized by symptoms and signs of degeneration of upper and lower motor neurons;
  • diagnostic criteria for ALS;
  • diagnosing ALS, being straightforward - patient showing progressive, generalized symptoms in bulbar and limb regions;
  • diagnosing ALS in bulbar and limb regions;
  • better patient/caregiver satisfaction - when effective communication strategies are used;
  • patients with ALS, should be followed in specialist multidisciplinary clinics;
  • likelihood of a peaceful death process - to be communicated to patients and their caregivers/relatives (GPP);
  • use of complementary and alternative medicine (CAM) - frequent in ALS;
  • patients with ALS - having increased risk of deep venous thrombosis (DVT)


This chapter contains sections titled:

  • Introduction

  • Search strategy

  • Results

  • References