Chapter 34. Cerebral Venous and Sinus Thrombosis

  1. Nils Erik Gilhus MD, PhD Professor7,
  2. Michael P. Barnes MD, FRCP Professor of Neurological Rehabilitation Medical Director8 and
  3. Michael Brainin MD Professor9
  1. K. Einhäupl1,
  2. J. Stam2,
  3. M.-G. Bousser3,
  4. S. F. T. M. de Bruijn4,
  5. J. M. Ferro5,
  6. I. Martinelli6 and
  7. F. Masuhr1

Published Online: 6 SEP 2010

DOI: 10.1002/9781444328394.ch34

European Handbook of Neurological Management, Second Edition, Volume 1, Second Edition

European Handbook of Neurological Management, Second Edition, Volume 1, Second Edition

How to Cite

Gilhus, N. E., Barnes, M. P. and Brainin, M. (2010) Cerebral Venous and Sinus Thrombosis, in European Handbook of Neurological Management, Second Edition, Volume 1, Second Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444328394.ch34

Author Information

  1. 7

    Department of Clinical Medicine, University of Bergen and Department of Neurology, Haukeland University Hospital, Bergen, Norway

  2. 8

    University of Newcastle, Hunters Moor Neurorehabilitation Ltd, Newcastle upon Tyne, UK

  3. 9

    Department of Clinical Medicine and Prevention, and Center for Clinical Neurosciences, Donau-Universität Krems, Department of Neurology, Landesklinikum Donauregion Tulln Tulln, Austria

Author Information

  1. 1

    Charité-Universitätsmedizin Berlin, Germany

  2. 2

    Academic Medical Centre Amsterdam, The Netherlands

  3. 3

    Hôpital Lariboisière, Paris, France

  4. 4

    Haga Hospital The Hague and LUMC, Leiden, The Netherlands

  5. 5

    Hospital Santa Maria, Lisboa, Portugal

  6. 6

    A. Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Maggiore Hospital, University of Milan, Italy

Publication History

  1. Published Online: 6 SEP 2010
  2. Published Print: 15 OCT 2010

ISBN Information

Print ISBN: 9781405185332

Online ISBN: 9781444328394



  • cerebral venous and sinus thrombosis;
  • cerebral venous and sinus thrombosis (CVST) - a rare condition;
  • Cranial computed tomography (CCT) alone - not sufficient, diagnosis established in combination with CT angiography;
  • syndrome of isolated intracranial hypertension (IIH) - with head ache, vomiting, and blurred vision due to papilloedema;
  • intra-arterial four-vessel angiography - gold standard for CVST diagnosis;
  • Cochrane Central Register of Controlled Trials (CENTRAL) and Cochrane Library;
  • oral anticoagulant therapy (OAT) - in patients with CVST, are not found;
  • symptomatic therapy - antiepileptic drugs, increased intracranial pressure management, psychomotor agitation control and analgesic treatment;
  • control of seizures - no data regarding effectiveness of prophylactic use of antiepileptic drugs (AED) in patients with CVST;
  • transtentorial brain herniation - frequent cause of death in patients with CVST


This chapter contains sections titled:

  • Background and objectives

  • Materials and methods

  • Treatment

  • Symptomatic treatment

  • References