39. Sleep Disorders in Neurodegenerative Disorders and Stroke

  1. Nils Erik Gilhus MD, PhD Professor15,
  2. Michael P. Barnes MD, FRCP Professor of Neurological Rehabilitation Medical Director16 and
  3. Michael Brainin MD Professor17
  1. P. Jennum1,
  2. J. Santamaria Cano2,
  3. C. Bassetti3,
  4. P. Clarenbach4,
  5. B. Högl5,
  6. J. Mathis6,
  7. R. Poirrier7,
  8. K. Sonka8,
  9. E. Svanborg9,
  10. L. Dolenc Groselj10,
  11. D. Kaynak11,
  12. M. Kruger12,
  13. A. Papavasiliou13 and
  14. Z. Zahariev14

Published Online: 6 SEP 2010

DOI: 10.1002/9781444328394.ch39

European Handbook of Neurological Management, Volume 1, Second Edition

European Handbook of Neurological Management, Volume 1, Second Edition

How to Cite

Gilhus, N. E., Barnes, M. P. and Brainin, M. (2010) Sleep Disorders in Neurodegenerative Disorders and Stroke, in European Handbook of Neurological Management, Volume 1, Second Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444328394.ch39

Author Information

  1. 15

    Department of Clinical Medicine, University of Bergen and Department of Neurology, Haukeland University Hospital, Bergen, Norway

  2. 16

    University of Newcastle, Hunters Moor Neurorehabilitation Ltd, Newcastle upon Tyne, UK

  3. 17

    Department of Clinical Medicine and Prevention, and Center for Clinical Neurosciences, Donau-Universität Krems, Department of Neurology, Landesklinikum Donauregion Tulln Tulln, Austria

Author Information

  1. 1

    Glostrup Hospital, University of Copenhagen, Denmark

  2. 2

    Hospital Clinic of Barcelona, Spain

  3. 3

    University Hospital Zurich, Switzerland

  4. 4

    Evangelisches Johannes - Krankenhaus, Germany

  5. 5

    Medical University of Innsbruck, Austria

  6. 6

    University Hospital, Inselspital, Bern, Switzerland

  7. 7

    CHU Sart Tilman, Liège, Belgium

  8. 8

    Charles University of Prague, Czech Republic

  9. 9

    Division of Clinical Neurophysiology, Linköping, Sweden

  10. 10

    University Medical Centre, Ljubljana, Slovenia

  11. 11

    Dokuz Eylu l University, Izmir, Turkey

  12. 12

    Hôpital de la Ville, Luxembourg

  13. 13

    Palia Pendeli Children's Hospital, Athens, Greece

  14. 14

    High Medical School, Plovdiv, Bulgaria

Publication History

  1. Published Online: 6 SEP 2010
  2. Published Print: 15 OCT 2010

ISBN Information

Print ISBN: 9781405185332

Online ISBN: 9781444328394



  • sleep disorders in neurodegenerative disorders and stroke;
  • sleep, active process generated and modulated - neural systems in hypothalamus, brainstem and thalamus;
  • sleep-disordered breathing (SDB);
  • EDS, not due to a sleep-related breathing disorder;
  • hypersomnias (EDS), inability to stay fully alert and awake - resulting in unintended lapses into sleep;
  • REM sleep behaviour disorder (RBD);
  • sleep-related movement disorders - relatively simple, stereotypic movements;
  • periodic limb movements (PLM), restless legs syndrome (RLS), bruxism, leg cramps, rhythmic movement disorders - and sleep-related movement disorders;
  • genetic neurodegenerative disorders;
  • treatment of sleep disorders in neurodegenerative diseases - complex, involving different strategies


This chapter contains sections titled:

  • Introduction

  • Search strategy

  • Method for reaching consensus

  • Sleep disorders

  • Management of sleep disorders in neurological diseases

  • References