99. Cartilage Injury

  1. Mohit Bhandari MD, PhD, FRCSC
  1. Joris E. J. Bekkers MD,
  2. Anika I. Tsuchida MD, PhD and
  3. Daniël B. F. Saris MD, PhD

Published Online: 31 OCT 2011

DOI: 10.1002/9781444345100.ch99

Evidence-Based Orthopedics

Evidence-Based Orthopedics

How to Cite

Bekkers, J. E. J., Tsuchida, A. I. and Saris, D. B. F. (2011) Cartilage Injury, in Evidence-Based Orthopedics (ed M. Bhandari), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345100.ch99

Editor Information

  1. Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada

Author Information

  1. University Medical Center Utrecht, Utrecht, The Netherlands

Publication History

  1. Published Online: 31 OCT 2011
  2. Published Print: 9 DEC 2011

ISBN Information

Print ISBN: 9781405184762

Online ISBN: 9781444345100



  • Articular cartilage;
  • Trauma;
  • MRI;
  • ACI;
  • Microfracturing;
  • OAT;
  • Prognosis;
  • Rehabilitation


The increasing young population presenting with knee trauma and related cartilage injury urges a detailed evaluation of articular cartilage damage followed by custom-made treatment plans to prevent development towards middle-aged osteoarthritis. MRI shows a moderate detection of clinically relevant articular cartilage lesions. Mid-term clinical outcomes favour cell-therapy over other cartilage surgeries. Increasing knowledge on rehabilitation after cartilage surgery will optimize protocols and further improve outcome after articular cartilage surgery with lower graft failure. Patient age, defect size, duration of symptoms and sports activity are factors that influence clinical outcome and pilot the development of an evidence-based treatment algorithm for focal articular cartilage lesions of the knee.