2. Hematopoiesis

  1. Alvin H. Schmaier MD and
  2. Hillard M. Lazarus MD, FACP
  1. Yuan Lin PhD1 and
  2. Stanton L. Gerson MD2

Published Online: 22 SEP 2011

DOI: 10.1002/9781444345254.ch2

Concise Guide to Hematology

Concise Guide to Hematology

How to Cite

Lin, Y. and Gerson, S. L. (2011) Hematopoiesis, in Concise Guide to Hematology (eds A. H. Schmaier and H. M. Lazarus), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345254.ch2

Editor Information

  1. Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA

Author Information

  1. 1

    Division of Hematology and Oncology, Case Western Reserve University, University Hospitals Case Medical Center, Seidman Cancer Center, Cleveland, OH, USA

  2. 2

    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA

Publication History

  1. Published Online: 22 SEP 2011
  2. Published Print: 4 NOV 2011

ISBN Information

Print ISBN: 9781405196666

Online ISBN: 9781444345254

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Keywords:

  • hematopoiesis;
  • hematopoietic stem cell (HSC);
  • BFU-E: burst forming unit-erythroid;
  • CFU: colony forming unit;
  • erythropoietin;
  • lymphopoiesis;
  • thrombopoiesis;
  • thrombopoietin;
  • stem cell surface markers

Summary

This chapter describes hematopoiesis in development and in the adult. It characterizes hematopoietic stem and progenitor cells and their functions. It also details mature hematopoietic cells and their functions. The hematopoietic microenvironment is described as it relates to cell development and the regulation of hematopoiesis. Last, abnormal hematopoiesis is discussed as it related to disease states.