4. Anemia: Clinical Approach
- Alvin H. Schmaier MD and
- Hillard M. Lazarus MD, FACP
Published Online: 22 SEP 2011
Copyright © 2012 Blackwell Publishing Ltd.
Concise Guide to Hematology
How to Cite
Marks, P. W. (2011) Anemia: Clinical Approach, in Concise Guide to Hematology (eds A. H. Schmaier and H. M. Lazarus), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345254.ch4
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
- Published Online: 22 SEP 2011
- Published Print: 4 NOV 2011
Print ISBN: 9781405196666
Online ISBN: 9781444345254
Anemia is a commonly encountered problem in clinical medicine. Broadly categorized, the causes of anemia relate to acute loss, inadequate production, or destruction of red blood cells. Thoughtful review of the complete blood count and reticulocyte count combined with examination of the peripheral blood smear leads to the creation of an appropriate differential diagnosis. The mean corpuscular volume, red cell distribution width, and reticulocyte count considered together provide particularly useful information, and sometimes point toward the specific cause of anemia present minimizing the amount of additional laboratory investigation required. Accurate and timely diagnosis facilitates appropriate therapeutic intervention.