12. Collodion Baby

  1. Alan D. Irvine MD, FRCPI, FRCP2,3,
  2. Peter H. Hoeger MD4,5 and
  3. Albert C. Yan MD, FAAP, FAAD6,7
  1. Edel A. O'Toole MB, PhD, FRCPI and
  2. David P. Kelsell BSc, PhD

Published Online: 24 MAY 2011

DOI: 10.1002/9781444345384.ch12

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

How to Cite

O'Toole, E. A. and Kelsell, D. P. (2011) Collodion Baby, in Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition (eds A. D. Irvine, P. H. Hoeger and A. C. Yan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345384.ch12

Editor Information

  1. 2

    Trinity College, Dublin, Ireland

  2. 3

    Our Lady's Children's Hospital, Dublin, Ireland

  3. 4

    University of Hamburg, Hamburg, Germany

  4. 5

    Catholic Children's Hospital Wilhelmstift, Hamburg, Germany

  5. 6

    University of Pennsylvania School of Medicine, Philadelphia, PA, USA

  6. 7

    The Children's Hospital of Philadelphia, Philadelphia, PA, USA

Author Information

  1. Centre for Cutaneous Research, Blizard Institute of Cell and Molecular Science, Bart's and the London School of Medicine and Dentistry, London, UK

Publication History

  1. Published Online: 24 MAY 2011
  2. Published Print: 3 JUN 2011

ISBN Information

Print ISBN: 9781405176958

Online ISBN: 9781444345384

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Keywords:

  • ARCI;
  • ATP-binding cassette transporter barrier;
  • collodion baby;
  • ichthyin;
  • ichthyosis;
  • lipoxygenase;
  • transglutaminase

Summary

The collodion baby is born covered in a yellowish, parchment-like membrane. The neonate has a striking appearance with ectropion and eclabion. The membrane subsequently falls off to reveal, in the majority of cases, a variant of autosomal recessive ichthyosiform erythroderma. This chapter discusses the molecular aetiology, clinical features and treatment of the collodion baby.