129. Tuberous Sclerosis

  1. Alan D. Irvine MD, FRCPI, FRCP3,4,
  2. Peter H. Hoeger MD5,6 and
  3. Albert C. Yan MD, FAAP, FAAD7,8
  1. John P. Osborne1 and
  2. Andrew J. Green2

Published Online: 24 MAY 2011

DOI: 10.1002/9781444345384.ch129

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

How to Cite

Osborne, J. P. and Green, A. J. (2011) Tuberous Sclerosis, in Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition (eds A. D. Irvine, P. H. Hoeger and A. C. Yan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345384.ch129

Editor Information

  1. 3

    Trinity College, Dublin, Ireland

  2. 4

    Our Lady's Children's Hospital, Dublin, Ireland

  3. 5

    University of Hamburg, Hamburg, Germany

  4. 6

    Catholic Children's Hospital Wilhelmstift, Hamburg, Germany

  5. 7

    University of Pennsylvania School of Medicine, Philadelphia, PA, USA

  6. 8

    The Children's Hospital of Philadelphia, Philadelphia, PA, USA

Author Information

  1. 1

    Department of Paediatrics, The Royal United Hospital, Bath, UK

  2. 2

    National Centre for Medical Genetics, Our Lady's Hospital, Dublin, Ireland

Publication History

  1. Published Online: 24 MAY 2011
  2. Published Print: 3 JUN 2011

ISBN Information

Print ISBN: 9781405176958

Online ISBN: 9781444345384

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Keywords:

  • tuberous sclerosis complex (TSC) - genetic condition, autosomal dominant trait;
  • TSC, variable condition - variations of disease, in families;
  • diagnostic features of TSC;
  • two TSC genes, tumour suppressor genes - clinical features of disease;
  • early facial erythema, boy of 18 months - infantile spasms, first year of life;
  • tuberous sclerosis complex, autosomal dominant - spontaneous mutation rate;
  • learning disorder, and TSC - not in seizure absence;
  • periungual fibromas, on nail top - or groove in nail;
  • cystic disease, clinically indistinguishable from ADPKD - from infancy;
  • patients with facial angiofibromatosis - cosmetic appearance, puberty and adult life

Summary

This chapter contains sections titled:

  • References