48. Herpes Simplex Virus Infections

  1. Alan D. Irvine MD, FRCPI, FRCP2,3,
  2. Peter H. Hoeger MD4,5 and
  3. Albert C. Yan MD, FAAP, FAAD6,7
  1. Helen M. Goodyear MBChB, FRCP, FRCPCH, MD, MMEd

Published Online: 24 MAY 2011

DOI: 10.1002/9781444345384.ch48

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

How to Cite

Goodyear, H. M. (2011) Herpes Simplex Virus Infections, in Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition (eds A. D. Irvine, P. H. Hoeger and A. C. Yan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345384.ch48

Editor Information

  1. 2

    Trinity College, Dublin, Ireland

  2. 3

    Our Lady's Children's Hospital, Dublin, Ireland

  3. 4

    University of Hamburg, Hamburg, Germany

  4. 5

    Catholic Children's Hospital Wilhelmstift, Hamburg, Germany

  5. 6

    University of Pennsylvania School of Medicine, Philadelphia, PA, USA

  6. 7

    The Children's Hospital of Philadelphia, Philadelphia, PA, USA

Author Information

  1. West Midlands Deanery, Heart of England NHS Foundation Trust, Birmingham, UK

Publication History

  1. Published Online: 24 MAY 2011
  2. Published Print: 3 JUN 2011

ISBN Information

Print ISBN: 9781405176958

Online ISBN: 9781444345384

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Keywords:

  • aciclovir;
  • genital infection;
  • gingivostomatitis;
  • herpes simplex virus;
  • HSV1;
  • HSV2;
  • HSV prevention;
  • HSV treatment;
  • whitlows

Summary

This chapter looks at the spectrum of herpes simplex virus infections in children, including gingivostomatitis, skin infections, whitlows and herpes genitalis. Disseminated herpes simplex virus infections and infections in immunocompromised children are also considered. Detailed information is given on herpes simplex virus aetiology, pathology, immunology and treatments. Modes of action of antiviral drugs are discussed, including newer agents as well as aciclovir. The chapter concludes by looking at prevention of herpes simplex virus infections, both primary and recurrent, including use of vaccination.