55. Skin Manifestations of Meningococcal Infection

  1. Alan D. Irvine MD, FRCPI, FRCP4,5,
  2. Peter H. Hoeger MD6,7 and
  3. Albert C. Yan MD, FAAP, FAAD8,9
  1. Saul N. Faust MA, MBBS, PhD, MRCPCH, FHEA1,
  2. Parviz Habibi PhD, FRCPCH2 and
  3. Robert S. Heyderman PhD, FRCP, DTM&H3

Published Online: 24 MAY 2011

DOI: 10.1002/9781444345384.ch55

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

How to Cite

Faust, S. N., Habibi, P. and Heyderman, R. S. (2011) Skin Manifestations of Meningococcal Infection, in Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition (eds A. D. Irvine, P. H. Hoeger and A. C. Yan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345384.ch55

Editor Information

  1. 4

    Trinity College, Dublin, Ireland

  2. 5

    Our Lady's Children's Hospital, Dublin, Ireland

  3. 6

    University of Hamburg, Hamburg, Germany

  4. 7

    Catholic Children's Hospital Wilhelmstift, Hamburg, Germany

  5. 8

    University of Pennsylvania School of Medicine, Philadelphia, PA, USA

  6. 9

    The Children's Hospital of Philadelphia, Philadelphia, PA, USA

Author Information

  1. 1

    Division of Infection, Inflammation and Immunity, University of Southampton, Southampton, UK

  2. 2

    Division of Medicine, Imperial College London, London, UK

  3. 3

    Wellcome Trust Tropical Centre, University of Liverpool, Liverpool, UK

Publication History

  1. Published Online: 24 MAY 2011
  2. Published Print: 3 JUN 2011

ISBN Information

Print ISBN: 9781405176958

Online ISBN: 9781444345384



  • skin manifestations - of meningococcal infection;
  • Neisseria meningitides, causes - severe infection in childhood;
  • Meningococcaemia, purpuric rash - vascular collapse and death;
  • meningococcal carriage - and invasion, rare following prolonged carriage;
  • meningococcal disease - a major health problem, worldwide;
  • molecular pathogenesis, disseminated intravascular coagulation - of bacterial septicaemia;
  • coagulation and fibronolytic pathways - endothelial proteins and protein complexes;
  • immunostaining for thrombomodulin - skin biopsy specimens, meningococcal sepsis;
  • meningococcal LPS release, trigger - inflammatory haemostatic processes, fulminant disease;
  • meningococcal disease, prevention - priority, focus of intense research effort


This chapter contains sections titled:

  • References