9. Acquired Neonatal Infections
- Alan D. Irvine MD, FRCPI, FRCP4,5,
- Peter H. Hoeger MD6,7 and
- Albert C. Yan MD, FAAP, FAAD8,9
Published Online: 24 MAY 2011
Copyright © 2011 Blackwell Publishing Ltd
Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition
How to Cite
Hartwig, N. G., Oranje, A. P., Van Gysel, D. and van Praag, M. C. G. (2011) Acquired Neonatal Infections, in Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition (eds A. D. Irvine, P. H. Hoeger and A. C. Yan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345384.ch9
Trinity College, Dublin, Ireland
Our Lady's Children's Hospital, Dublin, Ireland
University of Hamburg, Hamburg, Germany
Catholic Children's Hospital Wilhelmstift, Hamburg, Germany
University of Pennsylvania School of Medicine, Philadelphia, PA, USA
The Children's Hospital of Philadelphia, Philadelphia, PA, USA
- Published Online: 24 MAY 2011
- Published Print: 3 JUN 2011
Print ISBN: 9781405176958
Online ISBN: 9781444345384
Before birth, the fetus is living and developing in the sterile environment of the womb. The fetus is protected against infection by mechanical barriers like placenta and membranes and it benefits from maternal immunity. At birth, the newborn is readily colonized with micro-organisms of the birth canal and is confronted with a range of micro-organisms in the outside world. From that time onward, the neonate has to rely on the function of the immune system with additional protection of the mucous membranes and skin as essential barriers against hostile micro-organisms.
Common neonatal infections are listed in Table 9.1. Most of these topics are discussed extensively in other chapters as well.
In the neonatal period, defined as the age from birth to 4 weeks, acquired infections usually present with systemic symptoms and can lead to serious sequelae. The skin is frequently involved and may show petechiae, purpura, vesicles, pustules or a maculopapular rash. Many different micro-organisms may be associated (Table 9.2) although staphylococcal infections are most prominent.