97. Fibromatoses, Hyalinoses and Stiff Skin Syndrome

  1. Alan D. Irvine MD, FRCPI, FRCP5,6,
  2. Peter H. Hoeger MD7,8 and
  3. Albert C. Yan MD, FAAP, FAAD9,10
  1. Grazia Mancini1,
  2. Arnold P. Oranje MD, PhD2,
  3. Jan C. den Hollander3 and
  4. Moise L. Levy4

Published Online: 24 MAY 2011

DOI: 10.1002/9781444345384.ch97

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition

How to Cite

Mancini, G., Oranje, A. P., den Hollander, J. C. and Levy, M. L. (2011) Fibromatoses, Hyalinoses and Stiff Skin Syndrome, in Harper's Textbook of Pediatric Dermatology, Volume 1, 2, Third Edition (eds A. D. Irvine, P. H. Hoeger and A. C. Yan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444345384.ch97

Editor Information

  1. 5

    Trinity College, Dublin, Ireland

  2. 6

    Our Lady's Children's Hospital, Dublin, Ireland

  3. 7

    University of Hamburg, Hamburg, Germany

  4. 8

    Catholic Children's Hospital Wilhelmstift, Hamburg, Germany

  5. 9

    University of Pennsylvania School of Medicine, Philadelphia, PA, USA

  6. 10

    The Children's Hospital of Philadelphia, Philadelphia, PA, USA

Author Information

  1. 1

    Department of Neonatology, Wilhelmina Children's Hospital, UMC Utrecht, The Netherlands

  2. 2

    Department of Pediatrics, Erasmus MC, Sophia Children's Hospital, Rotterdam, The Netherlands

  3. 3

    Department of Radiology and Pathology, Erasmus MC, Rotterdam, The Netherlands

  4. 4

    Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA

Publication History

  1. Published Online: 24 MAY 2011
  2. Published Print: 3 JUN 2011

ISBN Information

Print ISBN: 9781405176958

Online ISBN: 9781444345384



  • fibromatoses, hyalinoses - and stiff skin syndrome;
  • differential diagnosis of benign spindle cell lesions - soft tissues in children;
  • benign fibromatoses of childhood;
  • fibromatosis, different meanings - self-limited condition;
  • terminology, and confusion - infantile digital fibromatosis, myofibroblastic proliferation;
  • key characteristic of myofibroma - zonal architecture, nodules;
  • fibromatoses - myofibroma/myofibromatosis;
  • myofibromas, appreciated - single subcutaneous or dermal nodule;
  • fibrous hamartoma of infancy - developmental anomaly, not a true neoplasm;
  • plantar-palmar fibromatosis, fibromatosis in palms or soles - Ledderhose disease


This chapter contains sections titled:

  • Fibromatoses

  • Hyalinoses

  • Stiff skin syndrome

  • References