14. The Chronic Liver Disease Patient

  1. John N. Plevris MD, PhD, FRCPE, FEBGH2 and
  2. Colin W. Howden MD, FRCP (Glasg.), FACP, AGAF, FACG3
  1. Joanna K. Dowman MBChB (Hons), MRCP and
  2. Phil N. Newsome PhD, FRCP

Published Online: 29 NOV 2011

DOI: 10.1002/9781444346381.ch14

Problem-Based Approach to Gastroenterology and Hepatology

Problem-Based Approach to Gastroenterology and Hepatology

How to Cite

Dowman, J. K. and Newsome, P. N. (2012) The Chronic Liver Disease Patient, in Problem-Based Approach to Gastroenterology and Hepatology (eds J. N. Plevris and C. W. Howden), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444346381.ch14

Editor Information

  1. 2

    Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK

  2. 3

    Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

Author Information

  1. NIHR Biomedical Research Unit and Centre for Liver Research, University of Birmingham, UK

Publication History

  1. Published Online: 29 NOV 2011
  2. Published Print: 17 JAN 2012

ISBN Information

Print ISBN: 9781405182270

Online ISBN: 9781444346381



  • cirrhosis;
  • liver biopsy;
  • alcohol;
  • imaging;
  • non-alcoholic fatty liver disease;
  • CT;
  • MRI;
  • hepatocellular carcinoma


This chapter details three cases of patients with chronic liver disease and illustrates many of the major issues facing the clinician. It highlights the differing causes of chronic liver disease, the ways in which severity of liver disease is calculated, and the strategies for investigation. The chapter also provides more detail on the management of specific liver conditions that are representative of the caseload seen in general hepatology.