7. Chronic Diarrhea and Malabsorption

  1. John N. Plevris MD, PhD, FRCPE, FEBGH2 and
  2. Colin W. Howden MD, FRCP (Glasg.), FACP, AGAF, FACG3
  1. Paul Beck MD, PhD, FRCPC,
  2. Remo Panaccione MD, FRCPC and
  3. Subrata Ghosh MBBS, MD (E din.), FRCP, FRCPE, FRCPC

Published Online: 29 NOV 2011

DOI: 10.1002/9781444346381.ch7

Problem-Based Approach to Gastroenterology and Hepatology

Problem-Based Approach to Gastroenterology and Hepatology

How to Cite

Beck, P., Panaccione, R. and Ghosh, S. (2012) Chronic Diarrhea and Malabsorption, in Problem-Based Approach to Gastroenterology and Hepatology (eds J. N. Plevris and C. W. Howden), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444346381.ch7

Editor Information

  1. 2

    Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK

  2. 3

    Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

Author Information

  1. Associate Professor of Medicine, Division of Gastroenterology, University of Calgary, Calgary, Alberta, Canada

Publication History

  1. Published Online: 29 NOV 2011
  2. Published Print: 17 JAN 2012

ISBN Information

Print ISBN: 9781405182270

Online ISBN: 9781444346381



  • chronic diarrhea, malabsorption;
  • Case 1, diarrhea and anemia;
  • recurrent mouth ulcerations;
  • iron deficiency anemia;
  • diarrhea with anemia;
  • celiac disease;
  • abdominal pain, diarrhea, weight loss;
  • abdominal discomfort, bloating;
  • Crohn's disease diagnosis;
  • anti-TNF treatment, healing benefits


Chronic diarrhea is a common and a challenging problem for clinicians. The differential diagnosis is vast and a systematic approach is required. Precise diagnosis should be achievable in most patients with true diarrhea. Acute or chronic diarrhea, osmotic or secretory diarrhea, large-volume or small-volume diarrhea, bloody or non-bloody diarrhea, and associated features will help to narrow down the investigations, so that the wide range of investigations available are not used in a haphazard manner.