9. Multisystem Disorders and Gastrointestinal Disease

  1. John N. Plevris MD, PhD, FRCPE, FEBGH1 and
  2. Colin W. Howden MD, FRCP (Glasg.), FACP, AGAF, FACG2
  1. Lynne A. Meekison MBChB and
  2. John N. Plevris MD, PhD, FRCPE, FEBGH

Published Online: 29 NOV 2011

DOI: 10.1002/9781444346381.ch9

Problem-Based Approach to Gastroenterology and Hepatology

Problem-Based Approach to Gastroenterology and Hepatology

How to Cite

Meekison, L. A. and Plevris, J. N. (2012) Multisystem Disorders and Gastrointestinal Disease, in Problem-Based Approach to Gastroenterology and Hepatology (eds J. N. Plevris and C. W. Howden), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444346381.ch9

Editor Information

  1. 1

    Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK

  2. 2

    Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

Author Information

  1. Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK

Publication History

  1. Published Online: 29 NOV 2011
  2. Published Print: 17 JAN 2012

ISBN Information

Print ISBN: 9781405182270

Online ISBN: 9781444346381

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Keywords:

  • multisystem disorders, gastrointestinal disease;
  • dysphagia, regurgitation, vomiting;
  • hemolytic syndromes (Zieve's syndrome);
  • liver disease;
  • reflux esophagitis with stricture;
  • stricturing adenocarcinoma;
  • esophageal manometry, pH study;
  • incomplete CREST syndrome and PBC;
  • cirrhosis complications;
  • HHT, autosomal dominant condition

Summary

Multisystem disorders often present with gastrointestinal symptoms, e.g. diarrhea and weight loss in a patient with thyrotoxicosis, whereas on other occasions gastrointestinal diseases can manifest with extra-gastrointestinal symptoms as the first presentation, e.g. in a case of enteropathic arthritis in inflammatory bowel disease. This chapter details two cases to illustrate such associations.