10. Energies for Focal Ablation: Cryoablation

  1. Hashim U Ahmed MRCS, BM, BCh, BA(Hons)2,
  2. Manit Arya FRCS, FRCS(Urol)3,
  3. Peter Carroll MD, MPH4 and
  4. Mark Emberton FRCS (Urol), FRCS, MD, MBBS, BSc2,5
  1. John F. Ward MD, FACS

Published Online: 10 NOV 2011

DOI: 10.1002/9781444346893.ch10

Focal Therapy in Prostate Cancer

Focal Therapy in Prostate Cancer

How to Cite

Ward, J. F. (2011) Energies for Focal Ablation: Cryoablation, in Focal Therapy in Prostate Cancer (eds H. U. Ahmed, M. Arya, P. Carroll and M. Emberton), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444346893.ch10

Editor Information

  1. 2

    Division of Surgery and Interventional Sciences, University College London, London, UK

  2. 3

    Department of Urology, University College London, London, UK

  3. 4

    Department of Urology, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA

  4. 5

    NIHR UCL/UCH Comprehensive Biomedical Research Centre, London, UK

Author Information

  1. Department of Urology, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA

Publication History

  1. Published Online: 10 NOV 2011
  2. Published Print: 2 OCT 2011

ISBN Information

Print ISBN: 9781405196499

Online ISBN: 9781444346893



  • cryoablation;
  • quality of life;
  • cryobiology;
  • ablative therapy;
  • outcome research


Cryotherapy—the ablation of tissue through the induction of extremely cold tissue temperatures—is the oldest of the ablative therapies currently used to achieve selective prostate tissue destruction. Therefore, most reports of subtotal prostate gland treatment for prostate cancer have employed cryoablation. This chapter reviews the history of cryotherapy, cryobiology, and the currently published literature supporting its use as an effective and safe means of treating prostate cancer.