13. In-Vitro Reproductive Technologies

  1. Emre Seli MD2,3,4
  1. Denny Sakkas PhD1,2

Published Online: 8 MAR 2011

DOI: 10.1002/9781444393958.ch13

Infertility

Infertility

How to Cite

Sakkas, D. (2011) In-Vitro Reproductive Technologies, in Infertility (ed E. Seli), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444393958.ch13

Editor Information

  1. 2

    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA

  2. 3

    Division of Reproductive Endocrinology and Infertility, Yale University School of Medicine, New Haven, Connecticut, USA

  3. 4

    Oocyte Donation and Gestational Surrogacy Program, Yale University School of Medicine, New Haven, Connecticut, USA

Author Information

  1. 1

    Molecular Biometrics Inc., New Haven, Connecticut, USA

  2. 2

    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA

Publication History

  1. Published Online: 8 MAR 2011
  2. Published Print: 23 MAR 2011

Book Series:

  1. Gynecology in Practice

Book Series Editors:

  1. Aydin Arici

ISBN Information

Print ISBN: 9781444333534

Online ISBN: 9781444393958

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Keywords:

  • in-vitro reproductive technologies;
  • IVF technologies - adapted to assisting infertile men;
  • ready-made micropipettes for injection - from commercial vendors;
  • nuclear maturity assessment;
  • microinjection techniques;
  • human oocyte, maternal mRNA - embryo reaching the four-to-eight cell stage;
  • embryo freezing, and cryopreservation - integral part of IVF clinics;
  • technique incorporation - treating difficult infertility patients, sparing embryo availability

Summary

In the 1960s there was a large increase in the different aspects of what we now have come to know as in-vitro fertilization (IVF), as our knowledge of ovarian stimulants, egg maturation, ovulation, fertilization, the growth of the embryo in vitro increased and laparoscopic techniques improved. In 1978, increased knowledge of the technologies culminated in the first IVF birth. The implementation of micromanipulation procedures such as ICSI, freezing technologies, and further understanding of stimulation have all led not only to increased pregnancy rates but to the treatment of both infertile and fertile patients.