15. Complications of Infertility Treatment

  1. Emre Seli MD3,4,5
  1. Luisa Delle Piane MD1,
  2. Alberto Revelli1,
  3. Sonya Kasyap MD, MSc Epi2,
  4. Mitchell Rosen MD, HCLD2 and
  5. Paolo F. Rinaudo MD, PhD2

Published Online: 8 MAR 2011

DOI: 10.1002/9781444393958.ch15



How to Cite

Delle Piane, L., Revelli, A., Kasyap, S., Rosen, M. and Rinaudo, P. F. (2011) Complications of Infertility Treatment, in Infertility (ed E. Seli), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444393958.ch15

Editor Information

  1. 3

    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA

  2. 4

    Division of Reproductive Endocrinology and Infertility, Yale University School of Medicine, New Haven, Connecticut, USA

  3. 5

    Oocyte Donation and Gestational Surrogacy Program, Yale University School of Medicine, New Haven, Connecticut, USA

Author Information

  1. 1

    Reproductive Medicine and IVF Unit, University of Turin, Torino, Italy

  2. 2

    Reproductive Endocrinology and Infertility, University of California San Francisco, California, USA

Publication History

  1. Published Online: 8 MAR 2011
  2. Published Print: 23 MAR 2011

Book Series:

  1. Gynecology in Practice

Book Series Editors:

  1. Aydin Arici

ISBN Information

Print ISBN: 9781444333534

Online ISBN: 9781444393958



  • infertility treatment complications;
  • assisted reproductive techniques (ART) - as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI);
  • acute complications - medication-related complications;
  • complications of infertility treatment;
  • risk factors for ovarian hyperstimulation syndrome (OHSS);
  • ART physicians, programs and patients - sharing responsibility, decreasing rate of multiple gestation after ART;
  • ovarian torsion - adnexal torsion, a true gynecologic emergency;
  • thromboembolic complications;
  • cyst rupture - women, experiencing ovarian cyst rupture at time of ovulation;
  • hormonal factors, involved - in female cancer etiology


Infertility treatment helps a large percentage of patients to fulfill their dreams of having a family. Nevertheless, a series of acute and long-term complications can occur. Acute complications can be related to ovulation induction or to the procedure of oocyte retrieval. Long-term effects include a higher incidence of pregnancy complications and, possibly, of imprinting disorders in the offspring.