5. Diagnosis and Management of Infertility due to Endometriosis

  1. Emre Seli MD1,2,3
  1. Janelle Luk MD1,2 and
  2. Hugh S. Taylor MD2

Published Online: 8 MAR 2011

DOI: 10.1002/9781444393958.ch5

Infertility

Infertility

How to Cite

Luk, J. and Taylor, H. S. (2011) Diagnosis and Management of Infertility due to Endometriosis, in Infertility (ed E. Seli), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444393958.ch5

Editor Information

  1. 1

    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA

  2. 2

    Division of Reproductive Endocrinology and Infertility, Yale University School of Medicine, New Haven, Connecticut, USA

  3. 3

    Oocyte Donation and Gestational Surrogacy Program, Yale University School of Medicine, New Haven, Connecticut, USA

Author Information

  1. 1

    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA

  2. 2

    Division of Reproductive Endocrinology and Infertility, Yale University School of Medicine, New Haven, Connecticut, USA

Publication History

  1. Published Online: 8 MAR 2011
  2. Published Print: 23 MAR 2011

Book Series:

  1. Gynecology in Practice

Book Series Editors:

  1. Aydin Arici

ISBN Information

Print ISBN: 9781444333534

Online ISBN: 9781444393958

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Keywords:

  • infertility, diagnosis and management - due to endometriosis;
  • endometriosis, gynecologic disease - affecting women of reproductive age;
  • retrograde menstruation theory - mechanism of histogenesis, as Sampson's theory;
  • coelomic metaplasia theory;
  • endometriosis, from metaplasia of cells - lining pelvic peritoneum;
  • embryonic rest theory;
  • immunologic dysfunction in peritoneal environment - inflammation, features of endometriotic tissue;
  • possible physical findings of endometriosis;
  • two main imaging modalities - utilized in diagnosing endometriosis, transvaginal ultrasonography (TUS) and MRI;
  • medical therapy, in pain management - associated with endometriosis

Summary

Endometriosis is a gynecologic medical condition in which endometrial-like cells appear and flourish in areas outside the uterine cavity. It is a disease with a wide spectrum of clinical presentation, ranging from women who appear asymptomatic to those who present with debilitating symptoms that significantly impair daily functioning and fertility. This chapter discusses up-to-date theories of the underlying pathogenesis of the disease, and most importantly, further explores the various ways of managing endometriosis in order to preserve fertility, or to alleviate the severity of presenting symptoms. With 10% of the female population being afflicted by endometriosis, it is imperative to be able to offer patients the various different medical and surgical treatments that are available for women who are afflicted by this challenging pathology.