7. Pre-Primary and Primary Prophylaxis: What Should We Do Next?

Pre-primary and Primary Prophylaxis

  1. Roberto de Franchis MD, AGAF Professor of Gastroenterology Head
  1. Roberto J Groszmann MD, FRCP Professor Senior Research Scientist1,2,
  2. Cristina Ripoll MD Research physician3 and
  3. Julio Vorobioff Associate Professor4

Published Online: 17 NOV 2010

DOI: 10.1002/9781444393989.ch7

Portal Hypertension V: Proceedings of the Fifth Baveno International Consensus Workshop, Fifth Edition

Portal Hypertension V: Proceedings of the Fifth Baveno International Consensus Workshop, Fifth Edition

How to Cite

Groszmann, R. J., Ripoll, C. and Vorobioff, J. (2011) Pre-Primary and Primary Prophylaxis: What Should We Do Next?, in Portal Hypertension V: Proceedings of the Fifth Baveno International Consensus Workshop, Fifth Edition (ed R. de Franchis), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444393989.ch7

Editor Information

  1. Department of Medical Sciences, University of Milan, and Gastroenterology 3 Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico Mangiagalli and Regina Elena Foundation, Milan, Italy

Author Information

  1. 1

    Yale University School of Medicine, New Haven, CT, USA

  2. 2

    VA Connecticut Healthcare System Digestive Diseases Section, West Haven, CT, USA

  3. 3

    Hepatology and Liver Transplant Unit, Digestive Diseases Department, Hospital General Universitario Gregorio Marañón, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain

  4. 4

    University of Rosario Medical School, Rosario, Argentina

Publication History

  1. Published Online: 17 NOV 2010
  2. Published Print: 14 JAN 2011

ISBN Information

Print ISBN: 9781444334494

Online ISBN: 9781444393989

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Keywords:

  • pre-primary and primary prophylaxis - What Should We Do Next?;
  • pre-primary prophylaxis, and patients without gastro-oesophageal varices;
  • non-selective beta-blockers (NSBBs);
  • HVPG reduction, based on decreasing portal venous inflow;
  • clinically significant portal hypertension - and incidence of varices and decompensation;
  • NSBBs, on hyperdynamic splanchnic circulation - for disease-specific treatment;
  • primary prophylaxis, beneficial effect of NSBBs - in primary prophylaxis;
  • physicians, using endoscopic variceal ligation - prevention of first variceal bleeding;
  • spectrum of liver disease in patients - setting of primary prophylaxis;
  • beta-blocker, like nebivolol - improving endothelial dysfunction

Summary

This chapter contains sections titled:

  • Introduction

  • Pre-primary prophylaxis

  • Primary prophylaxis

  • References

  • Pre-primary prophylaxis (prevention of the formation of varices)

  • Prevention of the first bleeding episode