19. BK Polyomavirus and Polyomavirus-Associated Nephropathy

  1. Deepali Kumar MD, MSc, FRCPC and
  2. Atul Humar MD, MSc, FRCPC
  1. Hans H. Hirsch MD, MSc, FMH (Inf Diseases), FMH (Internal Medicine), FAMH (Medical Microbiology)

Published Online: 5 MAY 2011

DOI: 10.1002/9781444397949.ch19

The AST Handbook of Transplant Infections

The AST Handbook of Transplant Infections

How to Cite

Hirsch, H. H. (2011) BK Polyomavirus and Polyomavirus-Associated Nephropathy, in The AST Handbook of Transplant Infections (eds D. Kumar and A. Humar), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444397949.ch19

Editor Information

  1. Transplant Infectious Diseases, University of Alberta, Edmonton, Canada

Author Information

  1. Institute for Medical Microbiology, Department of Biomedicine, University of Basel, Division of Infectious Diseases & Hospital Epidemiology, University Hospital Basel, Basel, Switzerland

Publication History

  1. Published Online: 5 MAY 2011
  2. Published Print: 13 MAY 2011

ISBN Information

Print ISBN: 9780470658277

Online ISBN: 9781444397949

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Keywords:

  • BK polyomavirus and polyomavirus-associated nephropathy;
  • screening, diagnosis and intervention - for polyomavirus-associated nephropathy (PyVAN) after renal transplantation;
  • screening for BK virus (BKV) replication - in kidney transplant recipients;
  • baseline allograft function;
  • qualitative DNA PCR;
  • cytology - high negative predictive value for viremia and PyVAN;
  • testing for BKV viremia;
  • quantitative DNA PCR;
  • screening for BKV replication - and PyVAN in non-kidney solid organ transplant (SOT) recipients;
  • treatment of BKV viremia or PyVAN - by modification of maintenance immunosuppression

Summary

This chapter contains sections titled:

  • Screening, diagnosis and intervention for polyomavirus-associated nephropathy (PyVAN) after renal transplantation

  • Screening for BK virus (BKV) replication in kidney transplant recipientsa

  • Screening for BKV replication and PyVAN in non-kidney solid organ transplant (SOT) recipients

  • Treatment of BKV viremia or PyVAN by modification of maintenance immunosuppression