26. Treatment of Nocardia Infections

  1. Deepali Kumar MD, MSc, FRCPC and
  2. Atul Humar MD, MSc, FRCPC
  1. Nina M. Clark MD

Published Online: 5 MAY 2011

DOI: 10.1002/9781444397949.ch26

The AST Handbook of Transplant Infections

The AST Handbook of Transplant Infections

How to Cite

Clark, N. M. (2011) Treatment of Nocardia Infections, in The AST Handbook of Transplant Infections (eds D. Kumar and A. Humar), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444397949.ch26

Editor Information

  1. Transplant Infectious Diseases, University of Alberta, Edmonton, Canada

Author Information

  1. Department of Internal Medicine, University of Illinois at Chicago, Chicago, IL, USA

Publication History

  1. Published Online: 5 MAY 2011
  2. Published Print: 13 MAY 2011

ISBN Information

Print ISBN: 9780470658277

Online ISBN: 9781444397949



  • treatment of nocardia infections;
  • pulmonary - mild to moderate;
  • amoxicillin-clavulanate and fluoroquinolones - few data to support use as initial therapy;
  • Meropenem IV 1g q8 h, successfully used - as alternative to imipenem for brain abscess;
  • pulmonary - severe;
  • cerebrale;
  • N. nova and N. otitidiscaviarum - resistant to sulfonamides;
  • TMP-SMX, sulfonamides such as sulfadiazine;
  • TMP-SMX, recommended by experts - as initial therapy for critically ill patients pending susceptibility testing;
  • TMP-SMX, trimethoprom-sulfamethoxazole